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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NBEAL2 All Species: 5.76
Human Site: S357 Identified Species: 11.52
UniProt: Q6ZNJ1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZNJ1 NP_055990.1 2754 302517 S357 R A P P E G D S D L A T R L L
Chimpanzee Pan troglodytes XP_525997 2750 313008 K381 K V A D K N E K D L A N K L L
Rhesus Macaque Macaca mulatta XP_001094456 2295 260424 V66 L P D N I L Q V L R I Q L L Q
Dog Lupus familis XP_541900 2305 251162 L76 S A G S V Q G L L G V V R G W
Cat Felis silvestris
Mouse Mus musculus Q6ZQA0 2742 301906 S356 R A P P E G D S D L A T W L L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508701 2269 259447 P40 D V D F E K L P T R V D D V P
Chicken Gallus gallus XP_421964 2298 259902 S69 W L D S F V S S Y E Q F L D V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W4E2 3584 396477 E388 A A A A T Q N E N D A A V G Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19317 2507 281187 S262 I A A L V A Y S I N V K Q T K
Sea Urchin Strong. purpuratus XP_785921 3355 375569 A190 L Q R A F V K A D V F T T L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_182078 2946 321916 D370 P A C T F E F D G E S S G L L
Baker's Yeast Sacchar. cerevisiae P25356 2167 250854
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.1 40.2 74.6 N.A. 88 N.A. N.A. 39.7 40.6 N.A. N.A. N.A. 20.7 N.A. 21.1 33.4
Protein Similarity: 100 65.6 56.3 77.1 N.A. 92 N.A. N.A. 53.8 55.7 N.A. N.A. N.A. 36.1 N.A. 37.4 48.8
P-Site Identity: 100 33.3 6.6 13.3 N.A. 93.3 N.A. N.A. 6.6 6.6 N.A. N.A. N.A. 13.3 N.A. 13.3 26.6
P-Site Similarity: 100 60 6.6 13.3 N.A. 93.3 N.A. N.A. 13.3 13.3 N.A. N.A. N.A. 26.6 N.A. 20 40
Percent
Protein Identity: N.A. N.A. N.A. 20.6 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 36.3 N.A.
P-Site Identity: N.A. N.A. N.A. 20 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 50 25 17 0 9 0 9 0 0 34 9 0 0 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 25 9 0 0 17 9 34 9 0 9 9 9 0 % D
% Glu: 0 0 0 0 25 9 9 9 0 17 0 0 0 0 0 % E
% Phe: 0 0 0 9 25 0 9 0 0 0 9 9 0 0 0 % F
% Gly: 0 0 9 0 0 17 9 0 9 9 0 0 9 17 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 9 0 0 0 9 0 9 0 0 0 0 % I
% Lys: 9 0 0 0 9 9 9 9 0 0 0 9 9 0 9 % K
% Leu: 17 9 0 9 0 9 9 9 17 25 0 0 17 50 42 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 9 9 0 9 9 0 9 0 0 0 % N
% Pro: 9 9 17 17 0 0 0 9 0 0 0 0 0 0 9 % P
% Gln: 0 9 0 0 0 17 9 0 0 0 9 9 9 0 17 % Q
% Arg: 17 0 9 0 0 0 0 0 0 17 0 0 17 0 0 % R
% Ser: 9 0 0 17 0 0 9 34 0 0 9 9 0 0 0 % S
% Thr: 0 0 0 9 9 0 0 0 9 0 0 25 9 9 0 % T
% Val: 0 17 0 0 17 17 0 9 0 9 25 9 9 9 9 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % W
% Tyr: 0 0 0 0 0 0 9 0 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _