KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NBEAL2
All Species:
9.39
Human Site:
S397
Identified Species:
18.79
UniProt:
Q6ZNJ1
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZNJ1
NP_055990.1
2754
302517
S397
C
I
M
S
D
S
P
S
A
K
E
V
F
K
E
Chimpanzee
Pan troglodytes
XP_525997
2750
313008
A421
A
V
M
N
K
S
P
A
A
K
E
V
F
K
E
Rhesus Macaque
Macaca mulatta
XP_001094456
2295
260424
N106
I
L
C
R
N
L
S
N
V
E
E
I
G
T
C
Dog
Lupus familis
XP_541900
2305
251162
R116
H
A
S
R
T
P
P
R
G
P
E
L
R
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQA0
2742
301906
S396
C
I
M
S
G
S
P
S
A
K
E
V
F
K
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508701
2269
259447
Q80
A
D
G
L
E
E
P
Q
Q
A
L
S
I
L
L
Chicken
Gallus gallus
XP_421964
2298
259902
Q109
V
L
R
L
Q
L
L
Q
C
V
Q
K
M
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4E2
3584
396477
S428
G
N
A
S
S
S
S
S
S
F
E
Q
L
R
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19317
2507
281187
A302
E
M
P
Q
H
D
S
A
D
V
F
F
S
F
P
Sea Urchin
Strong. purpuratus
XP_785921
3355
375569
Y230
A
I
L
N
G
S
L
Y
A
K
E
I
F
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_182078
2946
321916
A410
D
T
L
N
A
A
T
A
A
A
A
I
A
A
A
Baker's Yeast
Sacchar. cerevisiae
P25356
2167
250854
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.1
40.2
74.6
N.A.
88
N.A.
N.A.
39.7
40.6
N.A.
N.A.
N.A.
20.7
N.A.
21.1
33.4
Protein Similarity:
100
65.6
56.3
77.1
N.A.
92
N.A.
N.A.
53.8
55.7
N.A.
N.A.
N.A.
36.1
N.A.
37.4
48.8
P-Site Identity:
100
66.6
6.6
13.3
N.A.
93.3
N.A.
N.A.
6.6
0
N.A.
N.A.
N.A.
26.6
N.A.
0
53.3
P-Site Similarity:
100
86.6
40
20
N.A.
93.3
N.A.
N.A.
13.3
20
N.A.
N.A.
N.A.
40
N.A.
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.6
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.5
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
9
9
0
9
9
0
25
42
17
9
0
9
9
9
% A
% Cys:
17
0
9
0
0
0
0
0
9
0
0
0
0
0
9
% C
% Asp:
9
9
0
0
9
9
0
0
9
0
0
0
0
0
9
% D
% Glu:
9
0
0
0
9
9
0
0
0
9
59
0
0
0
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
9
9
34
9
0
% F
% Gly:
9
0
9
0
17
0
0
0
9
0
0
0
9
0
0
% G
% His:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
25
0
0
0
0
0
0
0
0
0
25
9
0
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
34
0
9
0
34
0
% K
% Leu:
0
17
17
17
0
17
17
0
0
0
9
9
9
9
17
% L
% Met:
0
9
25
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
9
0
25
9
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
9
42
0
0
9
0
0
0
0
9
% P
% Gln:
0
0
0
9
9
0
0
17
9
0
9
9
0
0
0
% Q
% Arg:
0
0
9
17
0
0
0
9
0
0
0
0
9
9
9
% R
% Ser:
0
0
9
25
9
42
25
25
9
0
0
9
9
9
0
% S
% Thr:
0
9
0
0
9
0
9
0
0
0
0
0
0
17
0
% T
% Val:
9
9
0
0
0
0
0
0
9
17
0
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _