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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NBEAL2
All Species:
7.58
Human Site:
S863
Identified Species:
15.15
UniProt:
Q6ZNJ1
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZNJ1
NP_055990.1
2754
302517
S863
N
N
I
C
L
D
L
S
P
S
H
G
L
D
G
Chimpanzee
Pan troglodytes
XP_525997
2750
313008
N877
I
C
L
D
L
S
T
N
C
L
H
G
R
L
T
Rhesus Macaque
Macaca mulatta
XP_001094456
2295
260424
L538
D
H
S
F
C
D
S
L
W
H
N
I
T
I
V
Dog
Lupus familis
XP_541900
2305
251162
G548
S
C
C
I
G
S
A
G
H
R
T
T
T
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQA0
2742
301906
S862
N
N
I
C
L
D
L
S
P
G
H
G
L
D
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508701
2269
259447
L512
L
I
A
L
Q
G
S
L
G
S
Q
S
M
S
S
Chicken
Gallus gallus
XP_421964
2298
259902
G541
Y
S
F
F
T
G
S
G
M
G
F
E
A
F
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4E2
3584
396477
D971
G
G
W
R
V
W
V
D
T
L
A
I
V
H
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19317
2507
281187
I736
Q
T
V
S
D
Y
T
I
E
E
R
P
E
N
F
Sea Urchin
Strong. purpuratus
XP_785921
3355
375569
S687
D
S
T
C
M
D
L
S
R
N
Q
P
Y
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_182078
2946
321916
S943
F
A
E
V
F
I
T
S
G
G
I
E
T
L
L
Baker's Yeast
Sacchar. cerevisiae
P25356
2167
250854
D410
I
S
S
T
K
Y
I
D
E
I
E
L
L
E
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.1
40.2
74.6
N.A.
88
N.A.
N.A.
39.7
40.6
N.A.
N.A.
N.A.
20.7
N.A.
21.1
33.4
Protein Similarity:
100
65.6
56.3
77.1
N.A.
92
N.A.
N.A.
53.8
55.7
N.A.
N.A.
N.A.
36.1
N.A.
37.4
48.8
P-Site Identity:
100
20
6.6
0
N.A.
93.3
N.A.
N.A.
6.6
0
N.A.
N.A.
N.A.
0
N.A.
0
40
P-Site Similarity:
100
33.3
26.6
6.6
N.A.
93.3
N.A.
N.A.
13.3
6.6
N.A.
N.A.
N.A.
20
N.A.
13.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.6
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.5
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
0
9
0
0
0
9
0
9
0
0
% A
% Cys:
0
17
9
25
9
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
17
0
0
9
9
34
0
17
0
0
0
0
0
25
0
% D
% Glu:
0
0
9
0
0
0
0
0
17
9
9
17
9
9
0
% E
% Phe:
9
0
9
17
9
0
0
0
0
0
9
0
0
9
9
% F
% Gly:
9
9
0
0
9
17
0
17
17
25
0
25
0
0
25
% G
% His:
0
9
0
0
0
0
0
0
9
9
25
0
0
9
0
% H
% Ile:
17
9
17
9
0
9
9
9
0
9
9
17
0
9
9
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
9
9
25
0
25
17
0
17
0
9
25
17
9
% L
% Met:
0
0
0
0
9
0
0
0
9
0
0
0
9
0
9
% M
% Asn:
17
17
0
0
0
0
0
9
0
9
9
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
17
0
0
17
0
0
0
% P
% Gln:
9
0
0
0
9
0
0
0
0
0
17
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
9
9
9
0
9
0
0
% R
% Ser:
9
25
17
9
0
17
25
34
0
17
0
9
0
9
17
% S
% Thr:
0
9
9
9
9
0
25
0
9
0
9
9
25
9
17
% T
% Val:
0
0
9
9
9
0
9
0
0
0
0
0
9
0
9
% V
% Trp:
0
0
9
0
0
9
0
0
9
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
17
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _