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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NBEAL2
All Species:
3.33
Human Site:
Y1346
Identified Species:
6.67
UniProt:
Q6ZNJ1
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZNJ1
NP_055990.1
2754
302517
Y1346
C
P
D
P
D
G
F
Y
H
A
L
S
P
F
C
Chimpanzee
Pan troglodytes
XP_525997
2750
313008
N1352
I
T
S
F
A
S
A
N
V
S
S
D
Q
W
S
Rhesus Macaque
Macaca mulatta
XP_001094456
2295
260424
T946
D
D
I
R
T
I
R
T
S
L
Y
G
L
I
K
Dog
Lupus familis
XP_541900
2305
251162
L956
A
L
D
L
L
L
A
L
L
Q
G
S
P
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQA0
2742
301906
Y1342
C
P
D
Q
D
A
F
Y
Q
A
L
S
P
F
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508701
2269
259447
K920
A
S
E
S
R
L
E
K
N
F
V
A
T
F
I
Chicken
Gallus gallus
XP_421964
2298
259902
L949
I
I
K
D
S
R
R
L
F
R
K
K
Y
G
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4E2
3584
396477
E1646
Q
S
A
G
M
T
I
E
D
E
D
Y
S
N
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19317
2507
281187
M1144
A
T
A
P
N
N
D
M
E
I
V
D
P
C
Q
Sea Urchin
Strong. purpuratus
XP_785921
3355
375569
E1968
S
L
D
Q
D
K
L
E
R
S
R
A
A
T
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_182078
2946
321916
K1434
S
L
S
S
D
S
G
K
V
P
L
D
I
L
A
Baker's Yeast
Sacchar. cerevisiae
P25356
2167
250854
A818
I
S
N
D
K
I
T
A
K
E
I
I
Y
L
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.1
40.2
74.6
N.A.
88
N.A.
N.A.
39.7
40.6
N.A.
N.A.
N.A.
20.7
N.A.
21.1
33.4
Protein Similarity:
100
65.6
56.3
77.1
N.A.
92
N.A.
N.A.
53.8
55.7
N.A.
N.A.
N.A.
36.1
N.A.
37.4
48.8
P-Site Identity:
100
0
0
20
N.A.
73.3
N.A.
N.A.
6.6
0
N.A.
N.A.
N.A.
0
N.A.
13.3
13.3
P-Site Similarity:
100
13.3
0
20
N.A.
73.3
N.A.
N.A.
33.3
0
N.A.
N.A.
N.A.
0
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.6
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.5
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
17
0
9
9
17
9
0
17
0
17
9
9
17
% A
% Cys:
17
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% C
% Asp:
9
9
34
17
34
0
9
0
9
0
9
25
0
0
0
% D
% Glu:
0
0
9
0
0
0
9
17
9
17
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
17
0
9
9
0
0
0
25
0
% F
% Gly:
0
0
0
9
0
9
9
0
0
0
9
9
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
25
9
9
0
0
17
9
0
0
9
9
9
9
9
9
% I
% Lys:
0
0
9
0
9
9
0
17
9
0
9
9
0
0
9
% K
% Leu:
0
25
0
9
9
17
9
17
9
9
25
0
9
17
0
% L
% Met:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
9
% M
% Asn:
0
0
9
0
9
9
0
9
9
0
0
0
0
9
0
% N
% Pro:
0
17
0
17
0
0
0
0
0
9
0
0
34
0
0
% P
% Gln:
9
0
0
17
0
0
0
0
9
9
0
0
9
0
25
% Q
% Arg:
0
0
0
9
9
9
17
0
9
9
9
0
0
0
0
% R
% Ser:
17
25
17
17
9
17
0
0
9
17
9
25
9
0
17
% S
% Thr:
0
17
0
0
9
9
9
9
0
0
0
0
9
9
0
% T
% Val:
0
0
0
0
0
0
0
0
17
0
17
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
0
0
17
0
0
9
9
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _