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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NBEAL2 All Species: 9.39
Human Site: Y580 Identified Species: 18.79
UniProt: Q6ZNJ1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZNJ1 NP_055990.1 2754 302517 Y580 G P A R A L R Y F D L T P S M
Chimpanzee Pan troglodytes XP_525997 2750 313008 Y598 S L E S A L Q Y F N L S H S M
Rhesus Macaque Macaca mulatta XP_001094456 2295 260424 K263 A L T A V M N K S P A A K E V
Dog Lupus familis XP_541900 2305 251162 L273 I L N E Q P V L M L M Q W L P
Cat Felis silvestris
Mouse Mus musculus Q6ZQA0 2742 301906 Y579 G P A R A L R Y F D L T P S M
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508701 2269 259447 L237 S P A T M E V L M R V L A D C
Chicken Gallus gallus XP_421964 2298 259902 S266 L Q A I F L N S N C F E H L I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W4E2 3584 396477 W683 H T L K Y Y Y W V V N P R A K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19317 2507 281187 M460 N S A F C G Q M G A M Y L F A
Sea Urchin Strong. purpuratus XP_785921 3355 375569 H407 E G K L S A H H Y F D F Q A D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_182078 2946 321916 D621 A E E S S I L D A D I G G Y T
Baker's Yeast Sacchar. cerevisiae P25356 2167 250854 S135 I L T L S N I S L I N K Q T L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.1 40.2 74.6 N.A. 88 N.A. N.A. 39.7 40.6 N.A. N.A. N.A. 20.7 N.A. 21.1 33.4
Protein Similarity: 100 65.6 56.3 77.1 N.A. 92 N.A. N.A. 53.8 55.7 N.A. N.A. N.A. 36.1 N.A. 37.4 48.8
P-Site Identity: 100 46.6 0 0 N.A. 100 N.A. N.A. 13.3 13.3 N.A. N.A. N.A. 0 N.A. 6.6 0
P-Site Similarity: 100 66.6 13.3 6.6 N.A. 100 N.A. N.A. 20 20 N.A. N.A. N.A. 20 N.A. 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. 20.6 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 36.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 42 9 25 9 0 0 9 9 9 9 9 17 9 % A
% Cys: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 9 % C
% Asp: 0 0 0 0 0 0 0 9 0 25 9 0 0 9 9 % D
% Glu: 9 9 17 9 0 9 0 0 0 0 0 9 0 9 0 % E
% Phe: 0 0 0 9 9 0 0 0 25 9 9 9 0 9 0 % F
% Gly: 17 9 0 0 0 9 0 0 9 0 0 9 9 0 0 % G
% His: 9 0 0 0 0 0 9 9 0 0 0 0 17 0 0 % H
% Ile: 17 0 0 9 0 9 9 0 0 9 9 0 0 0 9 % I
% Lys: 0 0 9 9 0 0 0 9 0 0 0 9 9 0 9 % K
% Leu: 9 34 9 17 0 34 9 17 9 9 25 9 9 17 9 % L
% Met: 0 0 0 0 9 9 0 9 17 0 17 0 0 0 25 % M
% Asn: 9 0 9 0 0 9 17 0 9 9 17 0 0 0 0 % N
% Pro: 0 25 0 0 0 9 0 0 0 9 0 9 17 0 9 % P
% Gln: 0 9 0 0 9 0 17 0 0 0 0 9 17 0 0 % Q
% Arg: 0 0 0 17 0 0 17 0 0 9 0 0 9 0 0 % R
% Ser: 17 9 0 17 25 0 0 17 9 0 0 9 0 25 0 % S
% Thr: 0 9 17 9 0 0 0 0 0 0 0 17 0 9 9 % T
% Val: 0 0 0 0 9 0 17 0 9 9 9 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 9 9 9 25 9 0 0 9 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _