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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGD5 All Species: 11.52
Human Site: S450 Identified Species: 31.67
UniProt: Q6ZNL6 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZNL6 NP_689749 1462 159907 S450 G E G G Q A A S D A L G G Y G
Chimpanzee Pan troglodytes XP_516303 1788 195413 S776 G E G G Q A A S D A L G G Y G
Rhesus Macaque Macaca mulatta XP_001106559 1431 160939 S426 D T D S N L S S D S T T V D G
Dog Lupus familis XP_541754 1465 161024 S452 E P E T Q A A S D T L S A Y G
Cat Felis silvestris
Mouse Mus musculus Q80UZ0 1219 134700 K276 D T S D E V R K I G I L P E G
Rat Rattus norvegicus NP_001102107 615 69102
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510070 1533 171433 N502 G E K G N Q A N H H S G D E G
Chicken Gallus gallus XP_414463 1677 186236 S683 T H K G Q T D S G A D H S K R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919894 1603 181792 S565 H Q V E C A S S E D Y V E I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.1 29.4 80 N.A. 65.2 27.9 N.A. 28.9 49 N.A. 40.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 81.3 46 86 N.A. 73.4 34.2 N.A. 46.3 61.7 N.A. 55.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 20 53.3 N.A. 6.6 0 N.A. 40 26.6 N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 53.3 N.A. 20 0 N.A. 46.6 26.6 N.A. 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 45 45 0 0 34 0 0 12 0 0 % A
% Cys: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 23 0 12 12 0 0 12 0 45 12 12 0 12 12 0 % D
% Glu: 12 34 12 12 12 0 0 0 12 0 0 0 12 23 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 34 0 23 45 0 0 0 0 12 12 0 34 23 0 78 % G
% His: 12 12 0 0 0 0 0 0 12 12 0 12 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 12 0 12 0 0 12 0 % I
% Lys: 0 0 23 0 0 0 0 12 0 0 0 0 0 12 0 % K
% Leu: 0 0 0 0 0 12 0 0 0 0 34 12 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 23 0 0 12 0 0 0 0 0 0 0 % N
% Pro: 0 12 0 0 0 0 0 0 0 0 0 0 12 0 0 % P
% Gln: 0 12 0 0 45 12 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 12 % R
% Ser: 0 0 12 12 0 0 23 67 0 12 12 12 12 0 0 % S
% Thr: 12 23 0 12 0 12 0 0 0 12 12 12 0 0 0 % T
% Val: 0 0 12 0 0 12 0 0 0 0 0 12 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 12 0 0 34 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _