KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C15orf58
All Species:
22.42
Human Site:
Y279
Identified Species:
41.11
UniProt:
Q6ZNW5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZNW5
NP_001013679
385
42362
Y279
R
V
C
R
A
T
D
Y
L
T
D
H
E
I
A
Chimpanzee
Pan troglodytes
XP_001168711
385
42199
Y279
R
V
C
R
A
T
D
Y
L
T
D
H
E
I
A
Rhesus Macaque
Macaca mulatta
XP_001096115
385
42409
Y279
R
V
C
R
A
T
D
Y
L
T
D
H
E
I
A
Dog
Lupus familis
XP_536194
385
42256
Y279
R
V
C
R
A
T
D
Y
L
T
D
H
E
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3TLS3
386
42496
Y280
R
V
C
R
A
T
D
Y
L
S
D
R
E
I
A
Rat
Rattus norvegicus
XP_218822
385
42285
Y279
R
V
C
Q
A
T
D
Y
L
S
D
H
E
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512648
336
36401
H234
G
V
C
R
V
A
A
H
L
A
E
G
E
I
A
Chicken
Gallus gallus
XP_429033
431
46400
R264
D
V
C
R
A
A
A
R
L
L
A
M
G
L
A
Frog
Xenopus laevis
A8E5Y3
399
45075
F296
N
I
C
K
V
T
D
F
L
V
A
K
N
I
A
Zebra Danio
Brachydanio rerio
Q08CA1
343
38973
V241
A
I
C
S
L
T
D
V
L
V
D
H
N
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786940
320
36490
H219
D
L
F
R
I
V
K
H
L
Q
D
R
D
I
A
Poplar Tree
Populus trichocarpa
XP_002302967
441
50048
F307
S
V
A
S
S
C
I
F
L
Q
N
N
N
I
P
Maize
Zea mays
NP_001150222
435
48388
W300
V
V
S
N
A
C
I
W
L
Q
D
N
N
V
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.8
81.8
N.A.
78.7
80.5
N.A.
56.6
44.3
45.3
49.8
N.A.
N.A.
N.A.
N.A.
33.2
Protein Similarity:
100
99.2
97.1
90.6
N.A.
87
88.8
N.A.
64.9
56.3
63.4
61.8
N.A.
N.A.
N.A.
N.A.
46.7
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
46.6
40
40
53.3
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
60
46.6
60
60
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
26.9
27.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.9
42.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
26.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
46.6
46.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
62
16
16
0
0
8
16
0
0
0
85
% A
% Cys:
0
0
77
0
0
16
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
0
0
0
62
0
0
0
70
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
0
54
0
0
% E
% Phe:
0
0
8
0
0
0
0
16
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
16
0
0
0
47
0
0
0
% H
% Ile:
0
16
0
0
8
0
16
0
0
0
0
0
0
85
0
% I
% Lys:
0
0
0
8
0
0
8
0
0
0
0
8
0
0
0
% K
% Leu:
0
8
0
0
8
0
0
0
100
8
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
0
0
0
8
16
31
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% P
% Gln:
0
0
0
8
0
0
0
0
0
24
0
0
0
0
0
% Q
% Arg:
47
0
0
62
0
0
0
8
0
0
0
16
0
0
0
% R
% Ser:
8
0
8
16
8
0
0
0
0
16
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
62
0
0
0
31
0
0
0
0
0
% T
% Val:
8
77
0
0
16
8
0
8
0
16
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _