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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDO2
All Species:
16.36
Human Site:
S22
Identified Species:
36
UniProt:
Q6ZQW0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZQW0
NP_919270.2
407
45424
S22
S
L
E
S
Y
H
I
S
E
E
Y
G
F
L
L
Chimpanzee
Pan troglodytes
XP_528116
347
38377
K10
L
L
S
C
Q
F
L
K
G
H
R
E
Q
R
L
Rhesus Macaque
Macaca mulatta
XP_001095833
421
47245
S36
S
L
E
R
Y
H
I
S
E
E
Y
G
F
L
L
Dog
Lupus familis
XP_539961
423
47530
S38
S
L
R
R
F
H
I
S
E
D
Y
G
F
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0V5
398
44421
P30
P
N
P
L
E
A
L
P
D
H
Y
K
P
W
M
Rat
Rattus norvegicus
Q9ERD9
407
45812
D22
I
L
E
E
Y
H
I
D
E
D
V
G
F
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516166
388
42890
I21
D
Y
R
P
W
M
E
I
A
S
N
L
P
Q
L
Chicken
Gallus gallus
XP_424397
362
39942
I20
S
R
Q
L
R
A
R
I
H
Q
M
P
Q
L
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001077323
435
48931
S20
S
L
R
K
F
H
I
S
E
E
Y
G
F
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782741
463
51327
S31
D
P
E
D
Y
H
A
S
H
L
Y
G
F
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47125
453
50757
Y49
T
R
L
S
S
K
K
Y
M
K
W
E
E
I
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83
82.4
75.8
N.A.
71.5
44.4
N.A.
66.8
54
N.A.
47.5
N.A.
N.A.
N.A.
N.A.
30.4
Protein Similarity:
100
83
86.4
84.4
N.A.
83.5
64.6
N.A.
78.3
66.3
N.A.
65.9
N.A.
N.A.
N.A.
N.A.
49.2
P-Site Identity:
100
13.3
93.3
73.3
N.A.
6.6
60
N.A.
6.6
13.3
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
20
93.3
86.6
N.A.
26.6
66.6
N.A.
13.3
26.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
19
10
0
10
0
0
0
0
10
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
10
0
0
0
10
10
19
0
0
0
0
0
% D
% Glu:
0
0
37
10
10
0
10
0
46
28
0
19
10
0
10
% E
% Phe:
0
0
0
0
19
10
0
0
0
0
0
0
55
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
55
0
0
0
% G
% His:
0
0
0
0
0
55
0
0
19
19
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
46
19
0
0
0
0
0
19
0
% I
% Lys:
0
0
0
10
0
10
10
10
0
10
0
10
0
0
0
% K
% Leu:
10
55
10
19
0
0
19
0
0
10
0
10
0
37
64
% L
% Met:
0
0
0
0
0
10
0
0
10
0
10
0
0
0
10
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
10
% N
% Pro:
10
10
10
10
0
0
0
10
0
0
0
10
19
0
0
% P
% Gln:
0
0
10
0
10
0
0
0
0
10
0
0
19
10
0
% Q
% Arg:
0
19
28
19
10
0
10
0
0
0
10
0
0
10
0
% R
% Ser:
46
0
10
19
10
0
0
46
0
10
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
10
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
10
0
0
10
0
% W
% Tyr:
0
10
0
0
37
0
0
10
0
0
55
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _