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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IDO2 All Species: 25.76
Human Site: S264 Identified Species: 56.67
UniProt: Q6ZQW0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZQW0 NP_919270.2 407 45424 S264 S Q E P L K Y S G G S A A Q S
Chimpanzee Pan troglodytes XP_528116 347 38377 F215 V L Q A F D E F L G I R H S K
Rhesus Macaque Macaca mulatta XP_001095833 421 47245 T278 S A S Q V A G T T G V H H H A
Dog Lupus familis XP_539961 423 47530 S280 S T E P L K Y S G G S A A Q S
Cat Felis silvestris
Mouse Mus musculus Q8R0V5 398 44421 S257 A T E P L K Y S G G S A A Q S
Rat Rattus norvegicus Q9ERD9 407 45812 S264 W D T P K K F S G G S A G Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516166 388 42890 S239 S A E P L K Y S G G S A A Q S
Chicken Gallus gallus XP_424397 362 39942 S228 S G G S A A Q S S V L H A F D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001077323 435 48931 S262 D D Q P M E F S G G S A A Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782741 463 51327 T276 S K E P F N F T G L S A A Q S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47125 453 50757 F281 A E G Q Y R I F S G G S N A Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83 82.4 75.8 N.A. 71.5 44.4 N.A. 66.8 54 N.A. 47.5 N.A. N.A. N.A. N.A. 30.4
Protein Similarity: 100 83 86.4 84.4 N.A. 83.5 64.6 N.A. 78.3 66.3 N.A. 65.9 N.A. N.A. N.A. N.A. 49.2
P-Site Identity: 100 6.6 13.3 93.3 N.A. 86.6 60 N.A. 93.3 20 N.A. 60 N.A. N.A. N.A. N.A. 60
P-Site Similarity: 100 13.3 33.3 93.3 N.A. 93.3 66.6 N.A. 93.3 20 N.A. 86.6 N.A. N.A. N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 51.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 19 0 10 10 19 0 0 0 0 0 64 64 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 19 0 0 0 10 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 10 46 0 0 10 10 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 19 0 28 19 0 0 0 0 0 10 0 % F
% Gly: 0 10 19 0 0 0 10 0 64 82 10 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 19 19 10 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % I
% Lys: 0 10 0 0 10 46 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 10 0 0 37 0 0 0 10 10 10 0 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 19 19 0 0 10 0 0 0 0 0 0 64 10 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % R
% Ser: 55 0 10 10 0 0 0 64 19 0 64 10 0 10 64 % S
% Thr: 0 19 10 0 0 0 0 19 10 0 0 0 0 0 0 % T
% Val: 10 0 0 0 10 0 0 0 0 10 10 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 37 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _