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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDO2
All Species:
25.45
Human Site:
S316
Identified Species:
56
UniProt:
Q6ZQW0
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZQW0
NP_919270.2
407
45424
S316
E
D
I
H
S
A
P
S
L
R
D
Y
I
L
S
Chimpanzee
Pan troglodytes
XP_528116
347
38377
A267
G
Q
D
H
L
L
T
A
Y
N
Q
C
V
Q
A
Rhesus Macaque
Macaca mulatta
XP_001095833
421
47245
S330
E
D
I
H
S
A
P
S
L
R
D
Y
V
L
S
Dog
Lupus familis
XP_539961
423
47530
S332
E
E
I
H
S
A
P
S
L
R
D
H
I
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0V5
398
44421
S309
E
D
L
H
V
A
P
S
L
R
D
Y
I
L
A
Rat
Rattus norvegicus
Q9ERD9
407
45812
S316
N
F
L
S
S
L
E
S
A
P
P
V
R
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516166
388
42890
S291
E
E
I
R
A
A
P
S
L
R
Q
H
I
L
S
Chicken
Gallus gallus
XP_424397
362
39942
S280
S
L
R
Q
H
I
L
S
S
A
D
P
Q
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001077323
435
48931
S314
Q
E
I
S
I
C
P
S
L
R
D
F
V
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782741
463
51327
S328
A
A
I
T
S
G
P
S
I
K
D
Y
I
H
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47125
453
50757
E333
Y
M
P
R
E
H
R
E
F
L
Y
H
L
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83
82.4
75.8
N.A.
71.5
44.4
N.A.
66.8
54
N.A.
47.5
N.A.
N.A.
N.A.
N.A.
30.4
Protein Similarity:
100
83
86.4
84.4
N.A.
83.5
64.6
N.A.
78.3
66.3
N.A.
65.9
N.A.
N.A.
N.A.
N.A.
49.2
P-Site Identity:
100
6.6
93.3
86.6
N.A.
80
13.3
N.A.
66.6
20
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
20
N.A.
86.6
20
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
10
46
0
10
10
10
0
0
0
0
19
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
28
10
0
0
0
0
0
0
0
64
0
0
0
0
% D
% Glu:
46
28
0
0
10
0
10
10
0
0
0
0
0
19
0
% E
% Phe:
0
10
0
0
0
0
0
0
10
0
0
10
0
0
10
% F
% Gly:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
46
10
10
0
0
0
0
0
28
0
10
0
% H
% Ile:
0
0
55
0
10
10
0
0
10
0
0
0
46
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
10
19
0
10
19
10
0
55
10
0
0
10
64
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
64
0
0
10
10
10
0
0
0
% P
% Gln:
10
10
0
10
0
0
0
0
0
0
19
0
10
10
10
% Q
% Arg:
0
0
10
19
0
0
10
0
0
55
0
0
10
0
10
% R
% Ser:
10
0
0
19
46
0
0
82
10
0
0
0
0
0
55
% S
% Thr:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
10
28
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
10
0
10
37
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _