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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IDO2 All Species: 14.85
Human Site: S323 Identified Species: 32.67
UniProt: Q6ZQW0 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZQW0 NP_919270.2 407 45424 S323 S L R D Y I L S S G Q D H L L
Chimpanzee Pan troglodytes XP_528116 347 38377 A274 A Y N Q C V Q A L A E L R S Y
Rhesus Macaque Macaca mulatta XP_001095833 421 47245 S337 S L R D Y V L S S G Q D H L L
Dog Lupus familis XP_539961 423 47530 S339 S L R D H I L S S G N D Q L L
Cat Felis silvestris
Mouse Mus musculus Q8R0V5 398 44421 A316 S L R D Y I L A S G P G D C L
Rat Rattus norvegicus Q9ERD9 407 45812 F323 S A P P V R E F V I L R R N E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516166 388 42890 S298 S L R Q H I L S S E N S Q L Y
Chicken Gallus gallus XP_424397 362 39942 R287 S S A D P Q L R E A F N H C V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001077323 435 48931 Q321 S L R D F V L Q Q A D E R L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782741 463 51327 S335 S I K D Y I H S S D S P E S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47125 453 50757 S340 E F L Y H L E S V C N I R E Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83 82.4 75.8 N.A. 71.5 44.4 N.A. 66.8 54 N.A. 47.5 N.A. N.A. N.A. N.A. 30.4
Protein Similarity: 100 83 86.4 84.4 N.A. 83.5 64.6 N.A. 78.3 66.3 N.A. 65.9 N.A. N.A. N.A. N.A. 49.2
P-Site Identity: 100 0 93.3 80 N.A. 66.6 6.6 N.A. 53.3 26.6 N.A. 40 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 26.6 100 86.6 N.A. 73.3 6.6 N.A. 60 40 N.A. 60 N.A. N.A. N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 51.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 0 0 0 19 0 28 0 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 10 0 0 0 19 0 % C
% Asp: 0 0 0 64 0 0 0 0 0 10 10 28 10 0 0 % D
% Glu: 10 0 0 0 0 0 19 0 10 10 10 10 10 10 10 % E
% Phe: 0 10 0 0 10 0 0 10 0 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 37 0 10 0 0 0 % G
% His: 0 0 0 0 28 0 10 0 0 0 0 0 28 0 0 % H
% Ile: 0 10 0 0 0 46 0 0 0 10 0 10 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 55 10 0 0 10 64 0 10 0 10 10 0 46 46 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 28 10 0 10 0 % N
% Pro: 0 0 10 10 10 0 0 0 0 0 10 10 0 0 0 % P
% Gln: 0 0 0 19 0 10 10 10 10 0 19 0 19 0 0 % Q
% Arg: 0 0 55 0 0 10 0 10 0 0 0 10 37 0 0 % R
% Ser: 82 10 0 0 0 0 0 55 55 0 10 10 0 19 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 10 28 0 0 19 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 10 37 0 0 0 0 0 0 0 0 0 28 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _