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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDO2
All Species:
19.09
Human Site:
T215
Identified Species:
42
UniProt:
Q6ZQW0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZQW0
NP_919270.2
407
45424
T215
R
L
S
I
Q
D
I
T
K
T
L
G
Q
M
H
Chimpanzee
Pan troglodytes
XP_528116
347
38377
Y166
Y
V
D
P
D
I
F
Y
A
V
I
R
I
F
L
Rhesus Macaque
Macaca mulatta
XP_001095833
421
47245
T229
R
L
S
I
Q
D
I
T
K
T
L
G
Q
M
H
Dog
Lupus familis
XP_539961
423
47530
T231
R
L
S
I
Q
D
I
T
R
T
L
G
Q
M
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0V5
398
44421
T208
R
L
S
I
Q
D
I
T
R
A
L
A
Q
M
H
Rat
Rattus norvegicus
Q9ERD9
407
45812
K215
A
A
S
L
E
K
A
K
E
I
F
K
R
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516166
388
42890
T190
A
G
S
I
D
E
M
T
W
A
L
R
Q
M
H
Chicken
Gallus gallus
XP_424397
362
39942
H179
D
K
A
L
Q
Q
M
H
D
Y
V
D
P
A
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001077323
435
48931
K213
C
Q
S
I
D
S
M
K
Q
A
L
K
R
M
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782741
463
51327
L227
V
H
K
M
R
N
T
L
N
R
M
S
E
G
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47125
453
50757
S232
A
A
T
I
E
R
L
S
K
A
L
M
E
M
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83
82.4
75.8
N.A.
71.5
44.4
N.A.
66.8
54
N.A.
47.5
N.A.
N.A.
N.A.
N.A.
30.4
Protein Similarity:
100
83
86.4
84.4
N.A.
83.5
64.6
N.A.
78.3
66.3
N.A.
65.9
N.A.
N.A.
N.A.
N.A.
49.2
P-Site Identity:
100
0
100
93.3
N.A.
80
13.3
N.A.
46.6
6.6
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
13.3
100
100
N.A.
86.6
40
N.A.
60
33.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
19
10
0
0
0
10
0
10
37
0
10
0
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
0
10
0
28
37
0
0
10
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
19
10
0
0
10
0
0
0
19
0
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
10
0
0
10
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
28
0
10
0
% G
% His:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
55
% H
% Ile:
0
0
0
64
0
10
37
0
0
10
10
0
10
0
0
% I
% Lys:
0
10
10
0
0
10
0
19
28
0
0
19
0
0
0
% K
% Leu:
0
37
0
19
0
0
10
10
0
0
64
0
0
0
10
% L
% Met:
0
0
0
10
0
0
28
0
0
0
10
10
0
73
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
10
0
0
46
10
0
0
10
0
0
0
46
0
0
% Q
% Arg:
37
0
0
0
10
10
0
0
19
10
0
19
19
0
10
% R
% Ser:
0
0
64
0
0
10
0
10
0
0
0
10
0
0
0
% S
% Thr:
0
0
10
0
0
0
10
46
0
28
0
0
0
0
0
% T
% Val:
10
10
0
0
0
0
0
0
0
10
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _