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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IDO2 All Species: 29.39
Human Site: T398 Identified Species: 64.67
UniProt: Q6ZQW0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZQW0 NP_919270.2 407 45424 T398 L K S V R D K T L E S I L H P
Chimpanzee Pan troglodytes XP_528116 347 38377 L339 K S V R D K T L E S I L H P R
Rhesus Macaque Macaca mulatta XP_001095833 421 47245 T412 L K S V R D K T L E S I L H P
Dog Lupus familis XP_539961 423 47530 T414 L K S V R D K T L E A I L H Q
Cat Felis silvestris
Mouse Mus musculus Q8R0V5 398 44421 T389 L K S V R E K T M E A L L C P
Rat Rattus norvegicus Q9ERD9 407 45812 T399 L R S V K D T T K K A L L S W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516166 388 42890 T379 L K S V R D T T K E A M I N R
Chicken Gallus gallus XP_424397 362 39942 S354 F L K S V R D S T R E G L I S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001077323 435 48931 T405 L K T V R N E T K D S S I S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782741 463 51327 T403 L K G L R D S T L R A M L R T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47125 453 50757 T441 L K Q C R D E T V A T A D I K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83 82.4 75.8 N.A. 71.5 44.4 N.A. 66.8 54 N.A. 47.5 N.A. N.A. N.A. N.A. 30.4
Protein Similarity: 100 83 86.4 84.4 N.A. 83.5 64.6 N.A. 78.3 66.3 N.A. 65.9 N.A. N.A. N.A. N.A. 49.2
P-Site Identity: 100 0 100 86.6 N.A. 66.6 40 N.A. 53.3 6.6 N.A. 40 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 6.6 100 93.3 N.A. 93.3 73.3 N.A. 80 13.3 N.A. 73.3 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 51.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 10 46 10 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 10 64 10 0 0 10 0 0 10 0 0 % D
% Glu: 0 0 0 0 0 10 19 0 10 46 10 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 28 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 28 19 19 0 % I
% Lys: 10 73 10 0 10 10 37 0 28 10 0 0 0 0 10 % K
% Leu: 82 10 0 10 0 0 0 10 37 0 0 28 64 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 19 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 28 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 10 0 10 73 10 0 0 0 19 0 0 0 10 19 % R
% Ser: 0 10 55 10 0 0 10 10 0 10 28 10 0 19 10 % S
% Thr: 0 0 10 0 0 0 28 82 10 0 10 0 0 0 10 % T
% Val: 0 0 10 64 10 0 0 0 10 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _