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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDO2
All Species:
20.91
Human Site:
Y253
Identified Species:
46
UniProt:
Q6ZQW0
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZQW0
NP_919270.2
407
45424
Y253
A
M
P
A
G
L
M
Y
E
G
V
S
Q
E
P
Chimpanzee
Pan troglodytes
XP_528116
347
38377
A204
K
Y
S
G
G
S
A
A
Q
S
T
V
L
Q
A
Rhesus Macaque
Macaca mulatta
XP_001095833
421
47245
D267
S
L
P
L
G
S
S
D
S
P
A
S
A
S
Q
Dog
Lupus familis
XP_539961
423
47530
Y269
A
M
P
V
G
L
T
Y
E
G
V
S
T
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0V5
398
44421
Y246
A
M
P
V
G
L
V
Y
E
G
A
A
T
E
P
Rat
Rattus norvegicus
Q9ERD9
407
45812
Y253
K
L
P
E
G
L
L
Y
E
G
V
W
D
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516166
388
42890
Y228
A
M
P
E
G
L
I
Y
E
G
I
S
A
E
P
Chicken
Gallus gallus
XP_424397
362
39942
P217
Y
E
G
V
S
E
Q
P
M
A
F
S
G
G
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001077323
435
48931
Y251
S
M
A
E
G
L
V
Y
E
G
V
D
D
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782741
463
51327
Y265
K
N
L
K
G
L
I
Y
E
G
V
S
K
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47125
453
50757
V270
H
M
G
L
P
Q
G
V
R
Y
G
A
E
G
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83
82.4
75.8
N.A.
71.5
44.4
N.A.
66.8
54
N.A.
47.5
N.A.
N.A.
N.A.
N.A.
30.4
Protein Similarity:
100
83
86.4
84.4
N.A.
83.5
64.6
N.A.
78.3
66.3
N.A.
65.9
N.A.
N.A.
N.A.
N.A.
49.2
P-Site Identity:
100
6.6
20
80
N.A.
66.6
53.3
N.A.
73.3
6.6
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
20
33.3
80
N.A.
80
66.6
N.A.
86.6
6.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
0
10
10
0
0
10
10
0
10
19
19
19
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
10
19
0
0
% D
% Glu:
0
10
0
28
0
10
0
0
64
0
0
0
10
46
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
19
10
82
0
10
0
0
64
10
0
10
19
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
19
0
0
0
10
0
0
0
0
% I
% Lys:
28
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
19
10
19
0
64
10
0
0
0
0
0
10
0
0
% L
% Met:
0
55
0
0
0
0
10
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
55
0
10
0
0
10
0
10
0
0
0
0
64
% P
% Gln:
0
0
0
0
0
10
10
0
10
0
0
0
10
19
19
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
19
0
10
0
10
19
10
0
10
10
0
55
0
10
10
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
10
0
19
10
0
% T
% Val:
0
0
0
28
0
0
19
10
0
0
46
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
10
10
0
0
0
0
0
64
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _