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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OTOG All Species: 9.09
Human Site: T659 Identified Species: 28.57
UniProt: Q6ZRI0 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZRI0 XP_002343092 2925 314794 T659 C G T F N G N T Q D D F L S P
Chimpanzee Pan troglodytes XP_521850 3112 333988 T847 C G T F N G N T Q D D F L S P
Rhesus Macaque Macaca mulatta XP_001085175 2223 250445 C63 C L G S V Y S C Y R S I S L F
Dog Lupus familis XP_854292 2384 268490 G225 L T L P Q T I G Q I F I E K L
Cat Felis silvestris
Mouse Mus musculus O55225 2910 313395 T646 C G T F N G N T Q D D F L S P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509761 1605 168085
Chicken Gallus gallus Q2PC93 5255 560538 A693 W D Q R D D F A T P A G D V E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_688274 3076 338876 I633 F L A P S G M I E S T P F L F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.6 31.9 28.6 N.A. 81.1 N.A. N.A. 28.5 21.7 N.A. 43.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 92.3 46.7 44.2 N.A. 86.2 N.A. N.A. 37.2 30.3 N.A. 60.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 6.6 N.A. 100 N.A. N.A. 0 0 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 6.6 N.A. 100 N.A. N.A. 0 6.6 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 0 0 0 13 0 0 13 0 0 0 0 % A
% Cys: 50 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % C
% Asp: 0 13 0 0 13 13 0 0 0 38 38 0 13 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 13 0 0 0 13 0 13 % E
% Phe: 13 0 0 38 0 0 13 0 0 0 13 38 13 0 25 % F
% Gly: 0 38 13 0 0 50 0 13 0 0 0 13 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 13 13 0 13 0 25 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % K
% Leu: 13 25 13 0 0 0 0 0 0 0 0 0 38 25 13 % L
% Met: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 38 0 38 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 25 0 0 0 0 0 13 0 13 0 0 38 % P
% Gln: 0 0 13 0 13 0 0 0 50 0 0 0 0 0 0 % Q
% Arg: 0 0 0 13 0 0 0 0 0 13 0 0 0 0 0 % R
% Ser: 0 0 0 13 13 0 13 0 0 13 13 0 13 38 0 % S
% Thr: 0 13 38 0 0 13 0 38 13 0 13 0 0 0 0 % T
% Val: 0 0 0 0 13 0 0 0 0 0 0 0 0 13 0 % V
% Trp: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 13 0 0 13 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _