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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM136
All Species:
36.67
Human Site:
S154
Identified Species:
73.33
UniProt:
Q6ZRR5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZRR5
NP_777586.1
245
27841
S154
R
E
T
G
H
Y
H
S
F
T
G
D
V
V
D
Chimpanzee
Pan troglodytes
XP_508819
334
37017
S243
R
E
T
G
H
Y
H
S
F
T
G
D
V
V
D
Rhesus Macaque
Macaca mulatta
XP_001106879
245
27907
S154
R
E
T
G
H
Y
H
S
F
T
G
D
V
V
D
Dog
Lupus familis
XP_546478
245
27916
S154
R
E
T
G
H
Y
H
S
F
T
G
D
V
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3TYE7
245
27687
S154
R
E
T
G
H
Y
H
S
F
T
G
D
V
V
D
Rat
Rattus norvegicus
NP_001101606
245
27609
S154
R
E
T
G
H
Y
H
S
F
T
G
D
V
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514279
312
34739
S221
R
E
T
G
R
Y
H
S
F
T
G
D
V
V
D
Chicken
Gallus gallus
XP_417891
244
27427
S153
R
E
M
G
C
Y
H
S
F
L
G
E
V
V
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LXV8
242
27287
S153
K
R
M
G
C
Y
D
S
L
A
G
D
V
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002325620
265
29872
R174
T
T
P
F
V
N
L
R
W
Y
L
D
V
A
G
Maize
Zea mays
NP_001143039
259
27697
T171
K
E
L
G
V
R
D
T
E
L
N
L
L
V
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567355
266
30189
S182
D
N
S
G
Q
K
G
S
K
A
Y
T
L
N
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.7
98.7
95
N.A.
92.2
91
N.A.
66.9
61.2
N.A.
56.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73
99.5
96.7
N.A.
95.5
95.5
N.A.
71.4
73
N.A.
70.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
73.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
80
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
27.1
27
N.A.
26.3
N.A.
N.A.
Protein Similarity:
43.4
44.7
N.A.
41.7
N.A.
N.A.
P-Site Identity:
13.3
26.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
20
46.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
17
0
0
0
9
0
% A
% Cys:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
17
0
0
0
0
75
0
0
84
% D
% Glu:
0
75
0
0
0
0
0
0
9
0
0
9
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
67
0
0
0
0
0
0
% F
% Gly:
0
0
0
92
0
0
9
0
0
0
75
0
0
0
17
% G
% His:
0
0
0
0
50
0
67
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
0
0
9
0
9
17
9
9
17
0
0
% L
% Met:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
9
0
0
0
0
9
0
0
9
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
67
9
0
0
9
9
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
0
0
0
0
84
0
0
0
0
0
0
0
% S
% Thr:
9
9
59
0
0
0
0
9
0
59
0
9
0
0
0
% T
% Val:
0
0
0
0
17
0
0
0
0
0
0
0
84
84
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
75
0
0
0
9
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _