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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM136
All Species:
20.3
Human Site:
S231
Identified Species:
40.61
UniProt:
Q6ZRR5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZRR5
NP_777586.1
245
27841
S231
H
A
W
R
S
R
R
S
E
E
R
Q
L
K
H
Chimpanzee
Pan troglodytes
XP_508819
334
37017
S320
H
A
W
R
S
R
R
S
E
E
W
Q
L
K
H
Rhesus Macaque
Macaca mulatta
XP_001106879
245
27907
S231
H
A
W
R
S
R
R
S
E
E
R
Q
L
K
H
Dog
Lupus familis
XP_546478
245
27916
S231
H
A
W
R
S
R
C
S
E
E
R
Q
L
K
H
Cat
Felis silvestris
Mouse
Mus musculus
Q3TYE7
245
27687
N231
H
A
W
R
S
R
R
N
E
E
R
Q
L
R
H
Rat
Rattus norvegicus
NP_001101606
245
27609
N231
H
A
W
R
S
R
R
N
E
E
R
Q
L
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514279
312
34739
S298
R
A
W
R
S
G
R
S
E
E
R
L
M
K
T
Chicken
Gallus gallus
XP_417891
244
27427
S230
H
S
W
R
R
L
R
S
E
D
A
P
V
K
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LXV8
242
27287
K230
R
R
W
K
E
Q
Y
K
L
D
G
V
N
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002325620
265
29872
K252
L
W
F
W
K
I
V
K
G
L
M
K
T
L
S
Maize
Zea mays
NP_001143039
259
27697
T248
K
K
P
L
P
P
P
T
T
P
P
K
L
A
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567355
266
30189
A258
L
I
K
T
L
S
K
A
K
T
S
G
M
K
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.7
98.7
95
N.A.
92.2
91
N.A.
66.9
61.2
N.A.
56.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73
99.5
96.7
N.A.
95.5
95.5
N.A.
71.4
73
N.A.
70.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
93.3
N.A.
86.6
86.6
N.A.
66.6
46.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
93.3
N.A.
100
100
N.A.
73.3
66.6
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
27.1
27
N.A.
26.3
N.A.
N.A.
Protein Similarity:
43.4
44.7
N.A.
41.7
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
20
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
0
0
0
0
0
9
0
0
9
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
67
59
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
9
0
9
9
0
9
0
% G
% His:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
59
% H
% Ile:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
9
9
9
0
9
17
9
0
0
17
0
59
9
% K
% Leu:
17
0
0
9
9
9
0
0
9
9
0
9
59
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
17
0
0
% M
% Asn:
0
0
0
0
0
0
0
17
0
0
0
0
9
0
0
% N
% Pro:
0
0
9
0
9
9
9
0
0
9
9
9
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
50
0
0
0
% Q
% Arg:
17
9
0
67
9
50
59
0
0
0
50
0
0
17
0
% R
% Ser:
0
9
0
0
59
9
0
50
0
0
9
0
0
0
9
% S
% Thr:
0
0
0
9
0
0
0
9
9
9
0
0
9
0
17
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
9
9
0
0
% V
% Trp:
0
9
75
9
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _