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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM136
All Species:
38.18
Human Site:
T71
Identified Species:
76.36
UniProt:
Q6ZRR5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZRR5
NP_777586.1
245
27841
T71
T
H
P
G
S
P
N
T
P
L
Q
V
H
V
L
Chimpanzee
Pan troglodytes
XP_508819
334
37017
T160
T
H
P
G
S
P
N
T
P
L
Q
V
H
V
L
Rhesus Macaque
Macaca mulatta
XP_001106879
245
27907
T71
T
H
P
G
S
P
N
T
P
L
Q
V
H
V
L
Dog
Lupus familis
XP_546478
245
27916
T71
T
H
P
G
S
P
N
T
P
L
Q
V
H
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3TYE7
245
27687
T71
T
H
P
G
S
P
N
T
P
L
Q
V
H
V
L
Rat
Rattus norvegicus
NP_001101606
245
27609
T71
T
H
P
G
S
P
N
T
P
L
Q
V
H
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514279
312
34739
T138
T
H
P
G
S
P
N
T
P
L
Q
V
H
V
L
Chicken
Gallus gallus
XP_417891
244
27427
T70
S
H
A
G
S
P
N
T
A
L
Q
V
H
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LXV8
242
27287
T70
T
H
P
G
T
E
N
T
Y
F
Q
I
L
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002325620
265
29872
S91
S
G
L
F
Y
E
D
S
R
D
E
L
V
V
N
Maize
Zea mays
NP_001143039
259
27697
S88
C
P
L
A
A
A
S
S
P
R
Q
M
K
A
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567355
266
30189
R99
S
V
I
N
S
T
T
R
L
S
E
S
V
M
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.7
98.7
95
N.A.
92.2
91
N.A.
66.9
61.2
N.A.
56.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73
99.5
96.7
N.A.
95.5
95.5
N.A.
71.4
73
N.A.
70.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
80
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
27.1
27
N.A.
26.3
N.A.
N.A.
Protein Similarity:
43.4
44.7
N.A.
41.7
N.A.
N.A.
P-Site Identity:
6.6
20
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
40
46.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
9
9
0
0
9
0
0
0
0
9
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
17
0
0
0
0
17
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
9
0
75
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
75
0
0
0
0
0
0
0
0
0
0
67
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
0
0
17
0
0
0
0
0
9
67
0
9
9
0
84
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% M
% Asn:
0
0
0
9
0
0
75
0
0
0
0
0
0
0
9
% N
% Pro:
0
9
67
0
0
67
0
0
67
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
84
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
9
9
0
0
0
0
0
% R
% Ser:
25
0
0
0
75
0
9
17
0
9
0
9
0
0
0
% S
% Thr:
67
0
0
0
9
9
9
75
0
0
0
0
0
9
0
% T
% Val:
0
9
0
0
0
0
0
0
0
0
0
67
17
75
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _