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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM136 All Species: 33.33
Human Site: Y152 Identified Species: 66.67
UniProt: Q6ZRR5 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZRR5 NP_777586.1 245 27841 Y152 F L R E T G H Y H S F T G D V
Chimpanzee Pan troglodytes XP_508819 334 37017 Y241 F L R E T G H Y H S F T G D V
Rhesus Macaque Macaca mulatta XP_001106879 245 27907 Y152 F L R E T G H Y H S F T G D V
Dog Lupus familis XP_546478 245 27916 Y152 F L R E T G H Y H S F T G D V
Cat Felis silvestris
Mouse Mus musculus Q3TYE7 245 27687 Y152 F L R E T G H Y H S F T G D V
Rat Rattus norvegicus NP_001101606 245 27609 Y152 F L R E T G H Y H S F T G D V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514279 312 34739 Y219 F L R E T G R Y H S F T G D V
Chicken Gallus gallus XP_417891 244 27427 Y151 F L R E M G C Y H S F L G E V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LXV8 242 27287 Y151 F L K R M G C Y D S L A G D V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002325620 265 29872 N172 E I T T P F V N L R W Y L D V
Maize Zea mays NP_001143039 259 27697 R169 M L K E L G V R D T E L N L L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567355 266 30189 K180 Y L D N S G Q K G S K A Y T L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.7 98.7 95 N.A. 92.2 91 N.A. 66.9 61.2 N.A. 56.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 73 99.5 96.7 N.A. 95.5 95.5 N.A. 71.4 73 N.A. 70.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 73.3 N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 80 N.A. 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 27.1 27 N.A. 26.3 N.A. N.A.
Protein Similarity: 43.4 44.7 N.A. 41.7 N.A. N.A.
P-Site Identity: 13.3 20 N.A. 20 N.A. N.A.
P-Site Similarity: 26.6 40 N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % A
% Cys: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 17 0 0 0 0 75 0 % D
% Glu: 9 0 0 75 0 0 0 0 0 0 9 0 0 9 0 % E
% Phe: 75 0 0 0 0 9 0 0 0 0 67 0 0 0 0 % F
% Gly: 0 0 0 0 0 92 0 0 9 0 0 0 75 0 0 % G
% His: 0 0 0 0 0 0 50 0 67 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 17 0 0 0 0 9 0 0 9 0 0 0 0 % K
% Leu: 0 92 0 0 9 0 0 0 9 0 9 17 9 9 17 % L
% Met: 9 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 9 0 0 0 0 9 0 0 % N
% Pro: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 67 9 0 0 9 9 0 9 0 0 0 0 0 % R
% Ser: 0 0 0 0 9 0 0 0 0 84 0 0 0 0 0 % S
% Thr: 0 0 9 9 59 0 0 0 0 9 0 59 0 9 0 % T
% Val: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 84 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 75 0 0 0 9 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _