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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM136
All Species:
21.21
Human Site:
Y32
Identified Species:
42.42
UniProt:
Q6ZRR5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZRR5
NP_777586.1
245
27841
Y32
H
L
N
K
H
R
S
Y
E
W
S
C
R
L
V
Chimpanzee
Pan troglodytes
XP_508819
334
37017
Y121
H
L
N
K
H
R
S
Y
E
W
S
C
R
L
V
Rhesus Macaque
Macaca mulatta
XP_001106879
245
27907
Y32
H
L
N
K
H
R
S
Y
E
W
S
C
R
L
V
Dog
Lupus familis
XP_546478
245
27916
Y32
R
L
N
K
H
R
S
Y
E
W
S
C
R
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3TYE7
245
27687
C32
C
L
N
K
H
R
S
C
E
W
S
C
R
L
V
Rat
Rattus norvegicus
NP_001101606
245
27609
C32
G
L
N
K
H
R
S
C
E
W
S
C
R
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514279
312
34739
Y99
F
L
N
K
H
R
G
Y
E
W
N
C
R
L
V
Chicken
Gallus gallus
XP_417891
244
27427
P31
L
W
N
R
H
R
S
P
E
W
N
C
R
L
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LXV8
242
27287
S31
H
L
N
S
G
R
D
S
E
W
N
C
R
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002325620
265
29872
L52
Y
F
K
G
Y
G
K
L
T
D
A
Q
K
V
E
Maize
Zea mays
NP_001143039
259
27697
S49
R
A
L
F
P
K
R
S
Y
D
F
C
N
R
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567355
266
30189
R60
V
R
M
E
W
N
N
R
G
F
S
T
F
H
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.7
98.7
95
N.A.
92.2
91
N.A.
66.9
61.2
N.A.
56.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73
99.5
96.7
N.A.
95.5
95.5
N.A.
71.4
73
N.A.
70.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
80
66.6
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
86.6
80
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
27.1
27
N.A.
26.3
N.A.
N.A.
Protein Similarity:
43.4
44.7
N.A.
41.7
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
13.3
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
17
% A
% Cys:
9
0
0
0
0
0
0
17
0
0
0
84
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
17
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
0
0
75
0
0
0
0
0
9
% E
% Phe:
9
9
0
9
0
0
0
0
0
9
9
0
9
0
0
% F
% Gly:
9
0
0
9
9
9
9
0
9
0
0
0
0
0
0
% G
% His:
34
0
0
0
67
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
59
0
9
9
0
0
0
0
0
9
0
0
% K
% Leu:
9
67
9
0
0
0
0
9
0
0
0
0
0
75
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
75
0
0
9
9
0
0
0
25
0
9
0
0
% N
% Pro:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
17
9
0
9
0
75
9
9
0
0
0
0
75
9
0
% R
% Ser:
0
0
0
9
0
0
59
17
0
0
59
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
75
% V
% Trp:
0
9
0
0
9
0
0
0
0
75
0
0
0
0
0
% W
% Tyr:
9
0
0
0
9
0
0
42
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _