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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRRC9 All Species: 1.82
Human Site: S1354 Identified Species: 4
UniProt: Q6ZRR7 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZRR7 NP_008949 1453 166911 S1354 N L Q M L D G S P V N S D D R
Chimpanzee Pan troglodytes XP_509984 1111 128143 H1018 I A V N Q E M H N L K G L C N
Rhesus Macaque Macaca mulatta XP_001095204 2201 254670 S2038 E Q Q L V E K S G E L L A L Q
Dog Lupus familis XP_547839 1687 192379 I1432 N L Q M L D G I P V N S D D R
Cat Felis silvestris
Mouse Mus musculus Q8CDN9 1456 167284 I1344 N L Q M L D G I P I N S D D R
Rat Rattus norvegicus XP_001077512 1460 168063 I1344 N L Q M L D G I P I N S D D R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517101 1373 156827 G1274 D V E V P G P G K V A P I K I
Chicken Gallus gallus XP_415403 2346 270651 N2097 H E Q K R E N N C L Q S D I A
Frog Xenopus laevis Q6NRC9 1030 118723 R937 E N K L I E E R D K S L Q C Q
Zebra Danio Brachydanio rerio NP_001107274 984 113434 L891 E G L E Y C H L L E E L S L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784143 1493 168392 I1353 N L L C I D G I P V T Q E E R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.5 20.2 72.6 N.A. 80.6 80.8 N.A. 60.5 20.3 20.3 33.5 N.A. N.A. N.A. N.A. 44.6
Protein Similarity: 100 75.9 36.4 78.5 N.A. 88.8 89.1 N.A. 73.4 35.1 38.3 46.5 N.A. N.A. N.A. N.A. 64.5
P-Site Identity: 100 0 13.3 93.3 N.A. 86.6 86.6 N.A. 6.6 20 0 0 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 13.3 40 93.3 N.A. 93.3 93.3 N.A. 33.3 46.6 40 0 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 0 10 0 10 0 10 % A
% Cys: 0 0 0 10 0 10 0 0 10 0 0 0 0 19 0 % C
% Asp: 10 0 0 0 0 46 0 0 10 0 0 0 46 37 0 % D
% Glu: 28 10 10 10 0 37 10 0 0 19 10 0 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 10 46 10 10 0 0 10 0 0 0 % G
% His: 10 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 19 0 0 37 0 19 0 0 10 10 10 % I
% Lys: 0 0 10 10 0 0 10 0 10 10 10 0 0 10 0 % K
% Leu: 0 46 19 19 37 0 0 10 10 19 10 28 10 19 0 % L
% Met: 0 0 0 37 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 46 10 0 10 0 0 10 10 10 0 37 0 0 0 19 % N
% Pro: 0 0 0 0 10 0 10 0 46 0 0 10 0 0 0 % P
% Gln: 0 10 55 0 10 0 0 0 0 0 10 10 10 0 19 % Q
% Arg: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 46 % R
% Ser: 0 0 0 0 0 0 0 19 0 0 10 46 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % T
% Val: 0 10 10 10 10 0 0 0 0 37 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _