KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC9
All Species:
16.06
Human Site:
T243
Identified Species:
35.33
UniProt:
Q6ZRR7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZRR7
NP_008949
1453
166911
T243
Q
I
K
E
L
A
D
T
T
A
M
K
K
I
M
Chimpanzee
Pan troglodytes
XP_509984
1111
128143
T34
V
G
Q
E
G
S
D
T
S
K
L
E
M
F
F
Rhesus Macaque
Macaca mulatta
XP_001095204
2201
254670
E271
F
E
R
F
S
L
E
E
V
E
R
L
E
R
D
Dog
Lupus familis
XP_547839
1687
192379
T345
Q
I
K
E
L
A
D
T
T
A
M
K
K
I
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDN9
1456
167284
S243
Q
I
K
E
L
A
D
S
T
A
M
K
K
I
M
Rat
Rattus norvegicus
XP_001077512
1460
168063
S243
Q
I
K
E
L
A
D
S
T
A
M
K
K
I
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517101
1373
156827
K219
M
Y
Y
N
M
R
V
K
T
V
Y
R
H
L
H
Chicken
Gallus gallus
XP_415403
2346
270651
R268
D
R
E
E
A
L
K
R
F
D
L
E
E
I
E
Frog
Xenopus laevis
Q6NRC9
1030
118723
Zebra Danio
Brachydanio rerio
NP_001107274
984
113434
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784143
1493
168392
A263
S
L
R
E
M
A
E
A
T
V
M
K
K
K
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.5
20.2
72.6
N.A.
80.6
80.8
N.A.
60.5
20.3
20.3
33.5
N.A.
N.A.
N.A.
N.A.
44.6
Protein Similarity:
100
75.9
36.4
78.5
N.A.
88.8
89.1
N.A.
73.4
35.1
38.3
46.5
N.A.
N.A.
N.A.
N.A.
64.5
P-Site Identity:
100
20
0
100
N.A.
93.3
93.3
N.A.
6.6
13.3
0
0
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
53.3
20
100
N.A.
100
100
N.A.
26.6
40
0
0
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
46
0
10
0
37
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
46
0
0
10
0
0
0
0
10
% D
% Glu:
0
10
10
64
0
0
19
10
0
10
0
19
19
0
10
% E
% Phe:
10
0
0
10
0
0
0
0
10
0
0
0
0
10
10
% F
% Gly:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% H
% Ile:
0
37
0
0
0
0
0
0
0
0
0
0
0
46
0
% I
% Lys:
0
0
37
0
0
0
10
10
0
10
0
46
46
10
0
% K
% Leu:
0
10
0
0
37
19
0
0
0
0
19
10
0
10
0
% L
% Met:
10
0
0
0
19
0
0
0
0
0
46
0
10
0
46
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
37
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
19
0
0
10
0
10
0
0
10
10
0
10
0
% R
% Ser:
10
0
0
0
10
10
0
19
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
28
55
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
10
0
10
19
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _