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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC9
All Species:
18.18
Human Site:
Y219
Identified Species:
40
UniProt:
Q6ZRR7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZRR7
NP_008949
1453
166911
Y219
N
Y
S
T
H
V
L
Y
H
L
P
C
L
Q
R
Chimpanzee
Pan troglodytes
XP_509984
1111
128143
E10
E
S
E
N
L
N
Q
E
E
I
I
K
E
L
C
Rhesus Macaque
Macaca mulatta
XP_001095204
2201
254670
L247
T
I
F
H
L
R
S
L
E
S
L
E
G
Q
P
Dog
Lupus familis
XP_547839
1687
192379
Y321
N
Y
S
T
H
V
L
Y
H
L
P
S
L
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDN9
1456
167284
Y219
N
Y
S
T
H
V
L
Y
H
L
P
S
L
Q
R
Rat
Rattus norvegicus
XP_001077512
1460
168063
Y219
N
Y
S
T
H
V
L
Y
H
L
P
S
L
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517101
1373
156827
S195
R
L
D
T
I
D
V
S
Q
K
P
I
K
E
M
Chicken
Gallus gallus
XP_415403
2346
270651
F244
H
Y
R
L
Y
I
I
F
H
L
R
A
L
E
N
Frog
Xenopus laevis
Q6NRC9
1030
118723
Zebra Danio
Brachydanio rerio
NP_001107274
984
113434
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784143
1493
168392
Y239
N
Y
S
T
H
V
L
Y
H
L
P
W
L
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.5
20.2
72.6
N.A.
80.6
80.8
N.A.
60.5
20.3
20.3
33.5
N.A.
N.A.
N.A.
N.A.
44.6
Protein Similarity:
100
75.9
36.4
78.5
N.A.
88.8
89.1
N.A.
73.4
35.1
38.3
46.5
N.A.
N.A.
N.A.
N.A.
64.5
P-Site Identity:
100
0
6.6
93.3
N.A.
93.3
93.3
N.A.
13.3
26.6
0
0
N.A.
N.A.
N.A.
N.A.
86.6
P-Site Similarity:
100
6.6
6.6
93.3
N.A.
93.3
93.3
N.A.
26.6
66.6
0
0
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% C
% Asp:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
10
0
0
0
0
10
19
0
0
10
10
28
0
% E
% Phe:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
10
0
0
10
46
0
0
0
55
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
10
10
0
0
10
10
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
10
10
0
0
% K
% Leu:
0
10
0
10
19
0
46
10
0
55
10
0
55
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
46
0
0
10
0
10
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
55
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
10
0
10
0
0
0
0
46
0
% Q
% Arg:
10
0
10
0
0
10
0
0
0
0
10
0
0
0
46
% R
% Ser:
0
10
46
0
0
0
10
10
0
10
0
28
0
0
0
% S
% Thr:
10
0
0
55
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
46
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
55
0
0
10
0
0
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _