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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC9
All Species:
17.58
Human Site:
Y251
Identified Species:
38.67
UniProt:
Q6ZRR7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZRR7
NP_008949
1453
166911
Y251
T
A
M
K
K
I
M
Y
Y
N
M
R
I
K
T
Chimpanzee
Pan troglodytes
XP_509984
1111
128143
L42
S
K
L
E
M
F
F
L
G
Y
P
R
I
V
G
Rhesus Macaque
Macaca mulatta
XP_001095204
2201
254670
L279
V
E
R
L
E
R
D
L
E
K
K
M
I
E
T
Dog
Lupus familis
XP_547839
1687
192379
Y353
T
A
M
K
K
I
M
Y
Y
N
M
R
I
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDN9
1456
167284
Y251
T
A
M
K
K
I
M
Y
Y
N
M
R
I
K
T
Rat
Rattus norvegicus
XP_001077512
1460
168063
Y251
T
A
M
K
K
I
M
Y
Y
N
M
R
I
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517101
1373
156827
E227
T
V
Y
R
H
L
H
E
E
L
E
K
L
K
E
Chicken
Gallus gallus
XP_415403
2346
270651
K276
F
D
L
E
E
I
E
K
L
E
R
E
L
E
N
Frog
Xenopus laevis
Q6NRC9
1030
118723
Zebra Danio
Brachydanio rerio
NP_001107274
984
113434
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784143
1493
168392
Y271
T
V
M
K
K
K
M
Y
Y
N
M
R
V
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.5
20.2
72.6
N.A.
80.6
80.8
N.A.
60.5
20.3
20.3
33.5
N.A.
N.A.
N.A.
N.A.
44.6
Protein Similarity:
100
75.9
36.4
78.5
N.A.
88.8
89.1
N.A.
73.4
35.1
38.3
46.5
N.A.
N.A.
N.A.
N.A.
64.5
P-Site Identity:
100
13.3
13.3
100
N.A.
100
100
N.A.
13.3
6.6
0
0
N.A.
N.A.
N.A.
N.A.
80
P-Site Similarity:
100
33.3
26.6
100
N.A.
100
100
N.A.
40
40
0
0
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
37
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
19
19
0
10
10
19
10
10
10
0
19
10
% E
% Phe:
10
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% G
% His:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
46
0
0
0
0
0
0
55
0
0
% I
% Lys:
0
10
0
46
46
10
0
10
0
10
10
10
0
55
0
% K
% Leu:
0
0
19
10
0
10
0
19
10
10
0
0
19
0
0
% L
% Met:
0
0
46
0
10
0
46
0
0
0
46
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
46
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
10
0
10
0
0
0
0
10
55
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
55
0
0
0
0
0
0
0
0
0
0
0
0
0
55
% T
% Val:
10
19
0
0
0
0
0
0
0
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
46
46
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _