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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRCAP All Species: 12.12
Human Site: S2220 Identified Species: 38.1
UniProt: Q6ZRS2 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZRS2 NP_006653.2 3230 343525 S2220 P L E E P S S S S V P S A P E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536900 3104 332016 S2097 P L E E P S G S S V P S A P E
Cat Felis silvestris
Mouse Mus musculus XP_001480453 3176 340176 S2159 P L E E P P G S S V S S V P E
Rat Rattus norvegicus XP_001080260 3212 343797 S2211 P L E E P P G S S V S S V P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396786 2758 308573 D1846 P L D D A D R D D L Q V S K A
Nematode Worm Caenorhab. elegans Q9NEL2 2395 268708 S1488 A V I D L D D S D S L L L N D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002303179 1682 192143 D775 S D W N P A M D Q Q A Q D R C
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_187887 2055 234029 L1148 P K I F L F I L S T R S G G V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 89.3 N.A. 85.2 87.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 20.8 22.5 N.A.
Protein Similarity: 100 N.A. N.A. 91.5 N.A. 88.3 90.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 35.4 37.8 N.A.
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 73.3 73.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 73.3 73.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 40 26.6 N.A.
Percent
Protein Identity: 20.9 N.A. N.A. 23.4 N.A. N.A.
Protein Similarity: 31.5 N.A. N.A. 36.1 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 20 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 0 13 13 0 0 0 0 13 0 25 0 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % C
% Asp: 0 13 13 25 0 25 13 25 25 0 0 0 13 0 13 % D
% Glu: 0 0 50 50 0 0 0 0 0 0 0 0 0 0 50 % E
% Phe: 0 0 0 13 0 13 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 38 0 0 0 0 0 13 13 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 25 0 0 0 13 0 0 0 0 0 0 0 0 % I
% Lys: 0 13 0 0 0 0 0 0 0 0 0 0 0 13 0 % K
% Leu: 0 63 0 0 25 0 0 13 0 13 13 13 13 0 0 % L
% Met: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 13 0 0 0 0 0 0 0 0 0 13 0 % N
% Pro: 75 0 0 0 63 25 0 0 0 0 25 0 0 50 0 % P
% Gln: 0 0 0 0 0 0 0 0 13 13 13 13 0 0 0 % Q
% Arg: 0 0 0 0 0 0 13 0 0 0 13 0 0 13 0 % R
% Ser: 13 0 0 0 0 25 13 63 63 13 25 63 13 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % T
% Val: 0 13 0 0 0 0 0 0 0 50 0 13 25 0 13 % V
% Trp: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _