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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GK5 All Species: 21.82
Human Site: S401 Identified Species: 40
UniProt: Q6ZS86 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZS86 NP_001034636.1 529 59168 S401 M G L K P S T S K Y H L V R A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112337 529 58933 S401 M G L K P S T S K Y H L V R A
Dog Lupus familis XP_542815 534 59669 N406 M G L K P S T N K Y H L V R A
Cat Felis silvestris
Mouse Mus musculus Q8BX05 534 59794 N406 M G L K H S T N K Y H L V R A
Rat Rattus norvegicus XP_001069076 635 69671 S507 M G L K H S T S K Y H L V R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509239 618 68864 N318 M G L K A S T N K C H L V R A
Chicken Gallus gallus Q5ZMJ4 517 57242 H396 K P T T T R N H L V R A I L E
Frog Xenopus laevis Q6GP95 479 52009 S368 G G I Y L V P S F S G L Q A P
Zebra Danio Brachydanio rerio A0JPE9 510 56468 T376 M G L K P S T T K R H L V R A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647763 556 62043 T430 I G L T P S T T K A H M V R A
Honey Bee Apis mellifera XP_392521 512 57267 R382 I G L K P T T R K N H L V R A
Nematode Worm Caenorhab. elegans NP_001024503 523 58507 T395 M C I R P D T T K V H M V R A
Sea Urchin Strong. purpuratus XP_787253 475 52657 V364 L E S I T Y R V K Q L Y D V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.7 83.9 N.A. 80.5 68.8 N.A. 33.8 61.6 59.9 61 N.A. 38.4 44.6 36.6 43.4
Protein Similarity: 100 N.A. 97.9 90 N.A. 88.3 75.4 N.A. 44.9 78.4 72.2 75 N.A. 57.3 63.5 56.5 61
P-Site Identity: 100 N.A. 100 93.3 N.A. 86.6 93.3 N.A. 80 0 20 86.6 N.A. 66.6 73.3 53.3 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 86.6 6.6 26.6 93.3 N.A. 86.6 86.6 80 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 8 0 8 0 8 77 % A
% Cys: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 16 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 8 77 0 0 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 16 0 0 8 0 0 77 0 0 0 0 % H
% Ile: 16 0 16 8 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 8 0 0 62 0 0 0 0 85 0 0 0 0 0 0 % K
% Leu: 8 0 70 0 8 0 0 0 8 0 8 70 0 8 0 % L
% Met: 62 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 24 0 8 0 0 0 0 0 % N
% Pro: 0 8 0 0 54 0 8 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % Q
% Arg: 0 0 0 8 0 8 8 8 0 8 8 0 0 77 0 % R
% Ser: 0 0 8 0 0 62 0 31 0 8 0 0 0 0 0 % S
% Thr: 0 0 8 16 16 8 77 24 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 8 0 8 0 16 0 0 77 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 8 0 0 0 39 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _