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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GK5
All Species:
27.27
Human Site:
Y421
Identified Species:
50
UniProt:
Q6ZS86
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZS86
NP_001034636.1
529
59168
Y421
A
F
R
N
K
Q
L
Y
E
M
M
K
K
E
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112337
529
58933
Y421
A
F
R
N
K
Q
L
Y
E
M
M
K
K
E
I
Dog
Lupus familis
XP_542815
534
59669
Y426
A
F
R
N
K
Q
L
Y
E
L
M
Q
K
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX05
534
59794
Y426
A
F
R
N
K
Q
L
Y
D
M
L
Q
R
E
I
Rat
Rattus norvegicus
XP_001069076
635
69671
Y527
A
F
R
N
K
Q
L
Y
D
M
L
Q
R
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509239
618
68864
Y451
A
F
R
N
K
Q
L
Y
E
M
M
Q
K
E
I
Chicken
Gallus gallus
Q5ZMJ4
517
57242
I416
N
K
Q
L
F
D
I
I
V
K
K
V
R
I
P
Frog
Xenopus laevis
Q6GP95
479
52009
L388
A
C
A
S
F
M
G
L
K
P
S
T
S
K
S
Zebra Danio
Brachydanio rerio
A0JPE9
510
56468
F396
A
F
R
N
K
Q
L
F
D
V
M
L
R
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647763
556
62043
I450
V
F
R
L
V
Q
L
I
E
A
A
E
K
E
T
Honey Bee
Apis mellifera
XP_392521
512
57267
Y402
V
F
G
M
L
L
L
Y
E
T
L
C
S
E
T
Nematode Worm
Caenorhab. elegans
NP_001024503
523
58507
Y415
A
F
R
V
Y
Q
I
Y
A
A
A
E
S
E
V
Sea Urchin
Strong. purpuratus
XP_787253
475
52657
R384
V
K
L
N
Q
V
I
R
V
D
G
G
V
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.7
83.9
N.A.
80.5
68.8
N.A.
33.8
61.6
59.9
61
N.A.
38.4
44.6
36.6
43.4
Protein Similarity:
100
N.A.
97.9
90
N.A.
88.3
75.4
N.A.
44.9
78.4
72.2
75
N.A.
57.3
63.5
56.5
61
P-Site Identity:
100
N.A.
100
86.6
N.A.
73.3
73.3
N.A.
93.3
0
6.6
60
N.A.
46.6
33.3
40
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
20
26.6
86.6
N.A.
53.3
40
60
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
8
0
0
0
0
0
8
16
16
0
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
24
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
47
0
0
16
0
77
0
% E
% Phe:
0
77
0
0
16
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
8
0
0
0
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
24
16
0
0
0
0
0
8
47
% I
% Lys:
0
16
0
0
54
0
0
0
8
8
8
16
39
8
0
% K
% Leu:
0
0
8
16
8
8
70
8
0
8
24
8
0
0
0
% L
% Met:
0
0
0
8
0
8
0
0
0
39
39
0
0
0
0
% M
% Asn:
8
0
0
62
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% P
% Gln:
0
0
8
0
8
70
0
0
0
0
0
31
0
0
8
% Q
% Arg:
0
0
70
0
0
0
0
8
0
0
0
0
31
0
0
% R
% Ser:
0
0
0
8
0
0
0
0
0
0
8
0
24
8
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
24
% T
% Val:
24
0
0
8
8
8
0
0
16
8
0
8
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _