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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPN12
All Species:
5.15
Human Site:
S429
Identified Species:
11.33
UniProt:
Q6ZSI9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZSI9
NP_653292.2
719
81037
S429
P
K
C
T
V
L
L
S
L
I
Q
R
N
R
R
Chimpanzee
Pan troglodytes
XP_001169048
714
81876
K426
F
V
L
A
L
M
Q
K
H
R
R
R
E
R
R
Rhesus Macaque
Macaca mulatta
XP_001114134
714
81832
K426
F
V
L
A
L
M
Q
K
H
R
R
R
E
R
R
Dog
Lupus familis
XP_541639
525
59144
T251
S
D
R
G
E
S
R
T
E
D
G
L
V
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER56
720
80570
S430
P
K
C
T
V
L
L
S
L
I
Q
R
N
R
R
Rat
Rattus norvegicus
Q78EJ9
703
79537
Q415
T
V
L
L
G
L
M
Q
K
N
R
R
R
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513498
700
79649
K414
F
L
V
G
L
I
Q
K
H
R
R
R
Q
R
K
Chicken
Gallus gallus
P00789
705
80333
Q416
S
F
L
V
A
L
M
Q
K
H
R
R
R
E
R
Frog
Xenopus laevis
NP_001080485
713
80989
K425
F
L
L
A
L
M
Q
K
N
K
R
K
E
R
R
Zebra Danio
Brachydanio rerio
XP_689397
704
80421
A412
E
G
C
T
F
L
V
A
L
M
Q
K
N
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VT65
925
103795
A626
G
K
C
T
A
I
V
A
L
M
Q
K
N
R
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.8
43.8
66.3
N.A.
86.1
42.7
N.A.
40.3
43.2
42.1
42.9
N.A.
31.1
N.A.
N.A.
N.A.
Protein Similarity:
100
60.7
61
68.4
N.A.
91.3
59.3
N.A.
58
59.2
59.9
58.8
N.A.
45.5
N.A.
N.A.
N.A.
P-Site Identity:
100
20
20
0
N.A.
100
13.3
N.A.
13.3
20
13.3
53.3
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
40
13.3
N.A.
100
40
N.A.
40
33.3
40
80
N.A.
86.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
28
19
0
0
19
0
0
0
0
0
0
0
% A
% Cys:
0
0
37
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
10
0
0
0
10
0
0
0
10
0
0
0
28
10
0
% E
% Phe:
37
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
19
10
0
0
0
0
0
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
28
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
19
0
0
0
19
0
0
0
0
0
% I
% Lys:
0
28
0
0
0
0
0
37
19
10
0
28
0
10
19
% K
% Leu:
0
19
46
10
37
46
19
0
37
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
28
19
0
0
19
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
10
0
0
37
0
0
% N
% Pro:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
37
19
0
0
37
0
10
10
0
% Q
% Arg:
0
0
10
0
0
0
10
0
0
28
55
64
19
73
73
% R
% Ser:
19
0
0
0
0
10
0
19
0
0
0
0
0
0
0
% S
% Thr:
10
0
0
37
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
28
10
10
19
0
19
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _