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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHISA6
All Species:
18.18
Human Site:
S442
Identified Species:
50
UniProt:
Q6ZSJ9
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZSJ9
NP_997269.2
500
55764
S442
V
L
D
R
Y
R
M
S
K
M
H
S
H
P
S
Chimpanzee
Pan troglodytes
XP_001153258
296
34049
S238
V
L
D
R
Y
R
M
S
K
M
H
S
H
P
S
Rhesus Macaque
Macaca mulatta
XP_001118293
928
101132
S870
V
L
D
R
Y
R
M
S
K
M
H
S
H
P
S
Dog
Lupus familis
XP_546625
264
29612
K207
L
D
R
Y
R
M
T
K
M
H
S
H
P
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH99
525
58407
T467
V
L
D
R
Y
R
M
T
K
M
H
S
H
P
S
Rat
Rattus norvegicus
XP_573113
521
58164
T463
V
L
D
R
Y
R
M
T
K
M
H
S
H
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516072
218
24251
A161
V
I
V
A
G
V
F
A
K
V
S
Y
D
K
A
Chicken
Gallus gallus
XP_001231791
203
23530
M146
D
R
Y
R
M
T
K
M
H
S
H
P
S
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002661135
294
33455
P237
M
M
K
M
H
S
H
P
S
S
S
N
H
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53
53.1
43.5
N.A.
90.8
91.1
N.A.
32.5
34.5
N.A.
27.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
57.2
53.3
48.4
N.A.
92
92.1
N.A.
37.2
37.5
N.A.
39.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
93.3
93.3
N.A.
13.3
20
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
40
20
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
12
0
0
0
0
0
12
23
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
56
0
0
0
0
0
0
0
0
0
12
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
12
0
12
0
12
12
67
12
67
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
0
12
12
67
0
0
0
0
12
0
% K
% Leu:
12
56
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
12
12
0
12
12
12
56
12
12
56
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% N
% Pro:
0
0
0
0
0
0
0
12
0
0
0
12
12
56
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
12
67
12
56
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
12
0
34
12
23
34
56
12
12
67
% S
% Thr:
0
0
0
0
0
12
12
23
0
0
0
0
0
0
0
% T
% Val:
67
0
12
0
0
12
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
12
56
0
0
0
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _