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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MFSD6 All Species: 24.24
Human Site: S416 Identified Species: 48.48
UniProt: Q6ZSS7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZSS7 NP_060164.3 791 88088 S416 P Q V E R N N S T E S S E E T
Chimpanzee Pan troglodytes XP_001166645 791 87868 S416 P Q V E R N N S T E S S E E T
Rhesus Macaque Macaca mulatta XP_001108155 793 88202 S418 P Q V E R N N S T E S S E E T
Dog Lupus familis XP_545567 795 87768 S420 P Q V E G N S S T E S S E E A
Cat Felis silvestris
Mouse Mus musculus Q8CBH5 775 86057 S419 P Q V E R D N S T E S S E E T
Rat Rattus norvegicus NP_001100381 794 87984 S419 P Q V E R D N S T E S S E E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521818 279 29754
Chicken Gallus gallus XP_421837 786 86648 N421 Q V D R N A S N E S S D N T P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LUQ4 793 88213 S427 E N V Q P R G S P G T R S T D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610983 762 83293 A403 M T C A I I S A S K I T F K Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_498662 630 68991 N290 D Y S D T F R N H P C P A E N
Sea Urchin Strong. purpuratus XP_787405 722 79257 T383 D E G R T P A T Y G T V A T Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.1 87.3 N.A. 83.8 87.9 N.A. 26.1 77.5 N.A. 56.1 N.A. 35.5 N.A. 27 23.7
Protein Similarity: 100 99.4 98.6 91 N.A. 88.6 91.4 N.A. 29.3 84.4 N.A. 71.2 N.A. 52.2 N.A. 44.5 40.7
P-Site Identity: 100 100 100 80 N.A. 93.3 93.3 N.A. 0 6.6 N.A. 13.3 N.A. 0 N.A. 6.6 0
P-Site Similarity: 100 100 100 86.6 N.A. 100 100 N.A. 0 20 N.A. 26.6 N.A. 40 N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 9 9 0 0 0 0 17 0 9 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 17 0 9 9 0 17 0 0 0 0 0 9 0 0 9 % D
% Glu: 9 9 0 50 0 0 0 0 9 50 0 0 50 59 0 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 9 0 9 0 9 0 0 17 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 9 0 0 0 0 9 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 9 34 42 17 0 0 0 0 9 0 9 % N
% Pro: 50 0 0 0 9 9 0 0 9 9 0 9 0 0 9 % P
% Gln: 9 50 0 9 0 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 0 0 0 17 42 9 9 0 0 0 0 9 0 0 0 % R
% Ser: 0 0 9 0 0 0 25 59 9 9 59 50 9 0 0 % S
% Thr: 0 9 0 0 17 0 0 9 50 0 17 9 0 25 42 % T
% Val: 0 9 59 0 0 0 0 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 9 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _