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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGEF18
All Species:
9.39
Human Site:
S1152
Identified Species:
29.52
UniProt:
Q6ZSZ5
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZSZ5
NP_001124427.1
1173
130814
S1152
L
P
G
P
P
A
P
S
P
L
P
A
T
P
L
Chimpanzee
Pan troglodytes
XP_001145436
782
87705
P762
P
G
P
P
A
P
S
P
L
P
A
T
P
L
S
Rhesus Macaque
Macaca mulatta
XP_001095927
1350
151137
S1329
L
P
G
P
P
A
P
S
P
L
P
A
T
P
L
Dog
Lupus familis
XP_854251
1117
124705
P1096
G
G
P
V
P
P
S
P
L
P
L
P
T
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9R4
1021
114326
S1001
P
P
V
S
P
A
S
S
L
P
T
T
P
L
A
Rat
Rattus norvegicus
NP_001100585
1184
132195
S1164
P
P
A
S
P
A
P
S
L
P
T
T
P
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418249
1012
115100
T992
A
H
A
Q
T
L
V
T
S
Q
P
T
L
L
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690750
1594
180523
T1573
L
P
K
T
H
N
Q
T
S
Q
Q
T
L
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.8
75.7
79.6
N.A.
70.4
73.4
N.A.
N.A.
56.6
N.A.
38.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
66.2
78.8
84.8
N.A.
76.1
80.2
N.A.
N.A.
67
N.A.
50.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
13.3
N.A.
26.6
40
N.A.
N.A.
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
13.3
N.A.
26.6
40
N.A.
N.A.
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
25
0
13
50
0
0
0
0
13
25
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
25
25
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
13
0
0
13
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
38
0
0
0
0
13
0
0
50
25
13
0
25
38
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
13
% N
% Pro:
38
63
25
38
63
25
38
25
25
50
38
13
38
50
13
% P
% Gln:
0
0
0
13
0
0
13
0
0
25
13
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
25
0
0
38
50
25
0
0
0
0
0
13
% S
% Thr:
0
0
0
13
13
0
0
25
0
0
25
63
38
13
13
% T
% Val:
0
0
13
13
0
0
13
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _