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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT14
All Species:
13.33
Human Site:
T179
Identified Species:
29.33
UniProt:
Q6ZU15
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZU15
NP_997249.2
432
50025
T179
L
K
S
L
D
L
L
T
M
K
N
L
D
S
K
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
R179
L
D
I
E
F
M
K
R
L
H
E
K
V
N
I
Rhesus Macaque
Macaca mulatta
XP_001085213
523
60991
T193
L
K
T
L
D
L
L
T
M
K
N
L
D
S
K
Dog
Lupus familis
XP_540501
432
50596
T179
L
K
S
L
D
L
L
T
M
K
N
I
D
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9DA97
420
48771
K185
N
I
I
P
L
I
A
K
A
D
S
L
S
K
N
Rat
Rattus norvegicus
Q5PQK1
456
53020
I180
S
L
D
N
K
V
N
I
I
P
L
I
A
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510590
457
52831
T186
L
K
S
L
D
L
V
T
M
K
K
L
D
S
K
Chicken
Gallus gallus
Q5ZMH1
349
40206
D142
L
N
R
R
H
I
I
D
N
R
V
H
C
C
F
Frog
Xenopus laevis
Q6AXA6
427
49720
I179
K
L
D
S
K
V
N
I
I
P
I
I
A
K
A
Zebra Danio
Brachydanio rerio
A4FUM1
423
49080
I179
K
L
D
S
K
V
N
I
I
P
I
I
A
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54359
419
48456
N179
K
K
L
D
S
K
V
N
I
I
P
V
I
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.9
56.9
82.1
N.A.
76.8
63.5
N.A.
59.7
37
62.5
60.6
N.A.
57.8
N.A.
N.A.
N.A.
Protein Similarity:
100
59.9
69.4
91.4
N.A.
89.5
76.9
N.A.
76.3
55.5
79.4
79.1
N.A.
75.9
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
93.3
N.A.
6.6
0
N.A.
86.6
6.6
0
0
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
20
20
N.A.
93.3
26.6
20
20
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
10
0
0
0
28
10
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% C
% Asp:
0
10
28
10
37
0
0
10
0
10
0
0
37
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
10
0
10
0
0
0
% H
% Ile:
0
10
19
0
0
19
10
28
37
10
19
37
10
0
10
% I
% Lys:
28
46
0
0
28
10
10
10
0
37
10
10
0
37
46
% K
% Leu:
55
28
10
37
10
37
28
0
10
0
10
37
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
37
0
0
0
0
0
0
% M
% Asn:
10
10
0
10
0
0
28
10
10
0
28
0
0
10
10
% N
% Pro:
0
0
0
10
0
0
0
0
0
28
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
10
0
0
0
10
0
10
0
0
0
0
0
% R
% Ser:
10
0
28
19
10
0
0
0
0
0
10
0
10
37
0
% S
% Thr:
0
0
10
0
0
0
0
37
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
28
19
0
0
0
10
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _