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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C14orf145
All Species:
21.82
Human Site:
T277
Identified Species:
48
UniProt:
Q6ZU80
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZU80
NP_689659.2
1094
128015
T277
I
K
N
K
L
R
Q
T
E
T
E
K
N
Q
L
Chimpanzee
Pan troglodytes
XP_522919
1094
128092
T277
I
K
N
K
L
R
Q
T
E
T
E
K
N
Q
L
Rhesus Macaque
Macaca mulatta
XP_001104541
1092
127884
T278
I
K
N
K
L
I
Q
T
E
T
E
K
N
Q
L
Dog
Lupus familis
XP_547936
1314
152397
T489
M
K
N
K
L
R
Q
T
E
T
E
K
S
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BI22
1102
128485
S276
I
K
R
K
L
R
Q
S
E
T
E
K
S
Q
L
Rat
Rattus norvegicus
P02563
1938
223490
S867
V
K
D
A
L
E
K
S
E
A
R
R
K
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O42184
1433
161009
V439
L
E
E
E
K
R
K
V
E
D
L
Q
F
R
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001083005
969
112677
R261
L
Q
K
M
D
D
M
R
S
Q
L
L
R
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q99323
2057
236625
A969
Y
E
R
K
Y
Q
Q
A
L
V
E
K
T
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P12844
1969
225491
T765
I
S
V
D
G
N
L
T
D
E
E
F
K
V
G
Sea Urchin
Strong. purpuratus
XP_790106
952
111519
Q244
E
L
R
S
R
L
I
Q
M
E
A
E
K
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
95.8
71
N.A.
78.1
21.2
N.A.
N.A.
21.2
N.A.
36.6
N.A.
20.8
N.A.
20.7
25.2
Protein Similarity:
100
99.2
97.2
77.5
N.A.
87.7
36.2
N.A.
N.A.
41.1
N.A.
58
N.A.
35.5
N.A.
36.3
47.9
P-Site Identity:
100
100
93.3
86.6
N.A.
80
26.6
N.A.
N.A.
13.3
N.A.
0
N.A.
33.3
N.A.
20
6.6
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
66.6
N.A.
N.A.
60
N.A.
13.3
N.A.
46.6
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
10
0
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
10
10
0
0
10
10
0
0
0
0
0
% D
% Glu:
10
19
10
10
0
10
0
0
64
19
64
10
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
46
0
0
0
0
10
10
0
0
0
0
0
0
10
0
% I
% Lys:
0
55
10
55
10
0
19
0
0
0
0
55
28
0
10
% K
% Leu:
19
10
0
0
55
10
10
0
10
0
19
10
0
0
64
% L
% Met:
10
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
37
0
0
10
0
0
0
0
0
0
28
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
10
55
10
0
10
0
10
0
55
0
% Q
% Arg:
0
0
28
0
10
46
0
10
0
0
10
10
10
10
0
% R
% Ser:
0
10
0
10
0
0
0
19
10
0
0
0
19
0
0
% S
% Thr:
0
0
0
0
0
0
0
46
0
46
0
0
10
10
0
% T
% Val:
10
0
10
0
0
0
0
10
0
10
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _