KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
All Species:
13.64
Human Site:
S249
Identified Species:
60
UniProt:
Q6ZUG5
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZUG5
NULL
572
66039
S249
R
T
L
Q
Q
I
L
S
A
F
K
V
R
V
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095053
597
68553
S249
R
T
L
Q
Q
I
L
S
A
F
K
M
R
V
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
XP_002726456
1265
143956
S838
Q
K
I
Q
Q
I
L
S
A
F
K
V
R
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414316
1077
121565
A568
H
L
I
R
T
S
L
A
T
L
K
L
K
S
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663836
1081
124348
S547
E
T
I
Q
R
V
L
S
G
H
I
I
S
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001191000
1008
114695
S391
H
I
V
E
A
A
L
S
T
Y
K
L
S
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
89.6
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
25.4
N.A.
20.5
N.A.
N.A.
N.A.
N.A.
22.5
Protein Similarity:
100
N.A.
92.4
N.A.
N.A.
N.A.
34.3
N.A.
N.A.
36.2
N.A.
33.2
N.A.
N.A.
N.A.
N.A.
36.4
P-Site Identity:
100
N.A.
93.3
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
N.A.
93.3
N.A.
N.A.
46.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
17
0
17
50
0
0
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
17
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% G
% His:
34
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% H
% Ile:
0
17
50
0
0
50
0
0
0
0
17
17
0
0
0
% I
% Lys:
0
17
0
0
0
0
0
0
0
0
84
0
17
0
34
% K
% Leu:
0
17
34
0
0
0
100
0
0
17
0
34
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
17
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
17
0
0
67
50
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
34
0
0
17
17
0
0
0
0
0
0
0
50
0
34
% R
% Ser:
0
0
0
0
0
17
0
84
0
0
0
0
34
17
0
% S
% Thr:
0
50
0
0
17
0
0
0
34
0
0
0
0
34
0
% T
% Val:
0
0
17
0
0
17
0
0
0
0
0
34
0
50
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _