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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FRMD7 All Species: 20.3
Human Site: S653 Identified Species: 44.67
UniProt: Q6ZUT3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZUT3 NP_919253.1 714 81614 S653 V A S E S S D S E S E I L K P
Chimpanzee Pan troglodytes XP_001142428 1045 118548 Q852 E K W V E D I Q M A I D L A E
Rhesus Macaque Macaca mulatta XP_001095803 714 81414 S653 V A S E S S D S E S E I L K P
Dog Lupus familis XP_549262 787 88688 S726 I G S E S S D S E S E I L K P
Cat Felis silvestris
Mouse Mus musculus A2AD83 703 80312 S642 V A S E S S D S E S E I I K P
Rat Rattus norvegicus Q9WTP0 879 98224 A796 V L T S T Y G A T A E T L S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506249 1047 119790 I854 M D K W I E D I Q M A I D L A
Chicken Gallus gallus XP_426268 693 77887 S632 S S T E S S D S D S D L L A A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio O57457 619 70690 S559 L V D P S G L S E E Q L K E I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P28191 1026 115075 F837 L A H T S S D F W V M V W E Q
Sea Urchin Strong. purpuratus XP_792466 1673 187206 Y1484 V A N C F T L Y G G N K T V V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.9 95.3 79 N.A. 85.1 23.8 N.A. 30.7 65.5 N.A. 24.2 N.A. N.A. N.A. 22.8 20.8
Protein Similarity: 100 44.7 96.5 82.8 N.A. 90 37.6 N.A. 44.8 75.9 N.A. 43.5 N.A. N.A. N.A. 38.5 30.2
P-Site Identity: 100 6.6 100 86.6 N.A. 93.3 20 N.A. 13.3 46.6 N.A. 20 N.A. N.A. N.A. 26.6 13.3
P-Site Similarity: 100 13.3 100 93.3 N.A. 100 46.6 N.A. 26.6 80 N.A. 46.6 N.A. N.A. N.A. 46.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 46 0 0 0 0 0 10 0 19 10 0 0 19 19 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 0 0 10 64 0 10 0 10 10 10 0 0 % D
% Glu: 10 0 0 46 10 10 0 0 46 10 46 0 0 19 10 % E
% Phe: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 10 10 0 10 10 0 0 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 10 0 10 10 0 0 10 46 10 0 10 % I
% Lys: 0 10 10 0 0 0 0 0 0 0 0 10 10 37 0 % K
% Leu: 19 10 0 0 0 0 19 0 0 0 0 19 55 10 0 % L
% Met: 10 0 0 0 0 0 0 0 10 10 10 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 37 % P
% Gln: 0 0 0 0 0 0 0 10 10 0 10 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 10 37 10 64 55 0 55 0 46 0 0 0 10 0 % S
% Thr: 0 0 19 10 10 10 0 0 10 0 0 10 10 0 10 % T
% Val: 46 10 0 10 0 0 0 0 0 10 0 10 0 10 10 % V
% Trp: 0 0 10 10 0 0 0 0 10 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _