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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FRMD7 All Species: 18.48
Human Site: S680 Identified Species: 40.67
UniProt: Q6ZUT3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZUT3 NP_919253.1 714 81614 S680 P M A R I R L S S G S L Q L D
Chimpanzee Pan troglodytes XP_001142428 1045 118548 P879 S P P D N K S P D E A T A A D
Rhesus Macaque Macaca mulatta XP_001095803 714 81414 S680 P M A R I R L S S G S L Q L D
Dog Lupus familis XP_549262 787 88688 S753 P M A R I R L S S G S L Q L D
Cat Felis silvestris
Mouse Mus musculus A2AD83 703 80312 S669 P R A R I R L S S G S L Q L E
Rat Rattus norvegicus Q9WTP0 879 98224 E823 G F S E T R I E K R I I I T G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506249 1047 119790 S881 S S P P D N K S P D E G M V D
Chicken Gallus gallus XP_426268 693 77887 S659 P R A R V R L S S G S L Q L E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio O57457 619 70690 P586 K I R H S H S P R S F G S T G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P28191 1026 115075 H864 E R G R V K C H Q Y W P R V F
Sea Urchin Strong. purpuratus XP_792466 1673 187206 M1511 M Q D I Q L A M S M C Q D D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.9 95.3 79 N.A. 85.1 23.8 N.A. 30.7 65.5 N.A. 24.2 N.A. N.A. N.A. 22.8 20.8
Protein Similarity: 100 44.7 96.5 82.8 N.A. 90 37.6 N.A. 44.8 75.9 N.A. 43.5 N.A. N.A. N.A. 38.5 30.2
P-Site Identity: 100 6.6 100 100 N.A. 86.6 6.6 N.A. 13.3 80 N.A. 0 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 20 100 100 N.A. 93.3 26.6 N.A. 20 93.3 N.A. 6.6 N.A. N.A. N.A. 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 46 0 0 0 10 0 0 0 10 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 10 10 10 0 0 0 10 10 0 0 10 10 46 % D
% Glu: 10 0 0 10 0 0 0 10 0 10 10 0 0 0 28 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 10 % F
% Gly: 10 0 10 0 0 0 0 0 0 46 0 19 0 0 19 % G
% His: 0 0 0 10 0 10 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 10 37 0 10 0 0 0 10 10 10 0 0 % I
% Lys: 10 0 0 0 0 19 10 0 10 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 46 0 0 0 0 46 0 46 0 % L
% Met: 10 28 0 0 0 0 0 10 0 10 0 0 10 0 0 % M
% Asn: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 46 10 19 10 0 0 0 19 10 0 0 10 0 0 0 % P
% Gln: 0 10 0 0 10 0 0 0 10 0 0 10 46 0 0 % Q
% Arg: 0 28 10 55 0 55 0 0 10 10 0 0 10 0 0 % R
% Ser: 19 10 10 0 10 0 19 55 55 10 46 0 10 0 0 % S
% Thr: 0 0 0 0 10 0 0 0 0 0 0 10 0 19 0 % T
% Val: 0 0 0 0 19 0 0 0 0 0 0 0 0 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _