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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA7
All Species:
10
Human Site:
S1221
Identified Species:
18.33
UniProt:
Q6ZV29
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZV29
NP_001092007.1
1317
145733
S1221
L
R
D
Q
Q
G
P
S
K
K
P
A
S
A
V
Chimpanzee
Pan troglodytes
XP_512331
1484
162976
D1383
L
T
D
R
R
S
T
D
L
N
E
S
R
R
A
Rhesus Macaque
Macaca mulatta
XP_001117679
626
69102
K531
R
D
Q
Q
G
P
S
K
R
P
S
S
E
V
L
Dog
Lupus familis
XP_537782
1344
148918
S1246
L
Q
D
R
Q
G
T
S
K
M
T
A
C
D
V
Cat
Felis silvestris
Mouse
Mus musculus
A2AJ88
1352
150476
S1243
L
Q
D
Q
Q
G
T
S
K
R
K
D
C
G
V
Rat
Rattus norvegicus
Q5BK26
1349
150006
S1240
L
Q
D
Q
Q
G
T
S
K
R
M
D
C
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124214
1324
147712
H1229
L
R
D
R
Q
E
T
H
K
T
K
T
S
D
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692276
1315
147148
E1212
M
K
D
Q
H
Q
E
E
F
H
K
S
R
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U969
1425
160554
P1245
N
Q
W
F
N
K
E
P
P
K
R
V
N
H
A
Honey Bee
Apis mellifera
XP_001120383
1324
149002
R1217
N
A
D
R
E
N
A
R
A
L
R
A
K
H
Q
Nematode Worm
Caenorhab. elegans
Q02331
1353
152377
K1235
G
D
E
K
E
T
R
K
F
K
R
Q
Q
S
R
Sea Urchin
Strong. purpuratus
XP_001202094
1454
161991
L1314
L
S
E
K
S
S
T
L
H
K
R
G
K
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S8J1
1515
167542
S1402
T
P
Q
A
F
G
D
S
L
S
G
V
W
A
F
Conservation
Percent
Protein Identity:
100
55.2
46
83.4
N.A.
80.1
80
N.A.
N.A.
73.4
N.A.
66.6
N.A.
40.9
47.9
33.5
45.8
Protein Similarity:
100
66.8
46.7
89.6
N.A.
87.1
86.8
N.A.
N.A.
83.5
N.A.
79.3
N.A.
60
65.4
49.8
61.8
P-Site Identity:
100
13.3
6.6
53.3
N.A.
53.3
53.3
N.A.
N.A.
40
N.A.
13.3
N.A.
6.6
13.3
6.6
13.3
P-Site Similarity:
100
33.3
26.6
66.6
N.A.
66.6
66.6
N.A.
N.A.
46.6
N.A.
40
N.A.
20
26.6
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
8
0
8
0
0
24
0
16
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
24
0
0
% C
% Asp:
0
16
62
0
0
0
8
8
0
0
0
16
0
16
0
% D
% Glu:
0
0
16
0
16
8
16
8
0
0
8
0
8
0
0
% E
% Phe:
0
0
0
8
8
0
0
0
16
0
0
0
0
0
8
% F
% Gly:
8
0
0
0
8
39
0
0
0
0
8
8
0
16
8
% G
% His:
0
0
0
0
8
0
0
8
8
8
0
0
0
16
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
16
0
8
0
16
39
31
24
0
16
0
0
% K
% Leu:
54
0
0
0
0
0
0
8
16
8
0
0
0
0
8
% L
% Met:
8
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% M
% Asn:
16
0
0
0
8
8
0
0
0
8
0
0
8
0
8
% N
% Pro:
0
8
0
0
0
8
8
8
8
8
8
0
0
8
0
% P
% Gln:
0
31
16
39
39
8
0
0
0
0
0
8
8
0
8
% Q
% Arg:
8
16
0
31
8
0
8
8
8
16
31
0
16
8
8
% R
% Ser:
0
8
0
0
8
16
8
39
0
8
8
24
16
16
0
% S
% Thr:
8
8
0
0
0
8
47
0
0
8
8
8
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
16
0
8
31
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _