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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA7
All Species:
16.97
Human Site:
S1258
Identified Species:
31.11
UniProt:
Q6ZV29
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZV29
NP_001092007.1
1317
145733
S1258
P
A
M
V
D
D
E
S
D
Y
Q
T
E
Y
E
Chimpanzee
Pan troglodytes
XP_512331
1484
162976
G1420
P
T
S
Y
V
S
D
G
C
A
D
G
E
E
S
Rhesus Macaque
Macaca mulatta
XP_001117679
626
69102
D568
A
M
V
D
D
E
S
D
Y
Q
T
E
Y
E
E
Dog
Lupus familis
XP_537782
1344
148918
S1283
V
A
T
V
D
D
E
S
D
Y
Q
T
E
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
A2AJ88
1352
150476
S1280
V
A
A
V
D
D
E
S
D
Y
Q
T
E
Y
E
Rat
Rattus norvegicus
Q5BK26
1349
150006
S1277
V
A
A
V
D
D
E
S
D
Y
Q
T
E
Y
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124214
1324
147712
S1266
A
A
V
A
D
D
E
S
D
Y
Q
T
E
Y
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692276
1315
147148
E1249
K
Q
A
V
V
D
E
E
S
E
Y
Q
T
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U969
1425
160554
S1282
V
N
T
A
E
L
F
S
E
D
E
D
C
D
G
Honey Bee
Apis mellifera
XP_001120383
1324
149002
D1254
S
R
G
S
I
Y
V
D
L
E
I
D
S
D
T
Nematode Worm
Caenorhab. elegans
Q02331
1353
152377
R1272
P
V
V
R
P
T
L
R
H
S
M
S
L
N
P
Sea Urchin
Strong. purpuratus
XP_001202094
1454
161991
E1351
Q
A
I
P
D
P
D
E
V
D
Y
A
R
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S8J1
1515
167542
G1439
L
A
Y
V
S
S
V
G
E
L
E
R
A
K
T
Conservation
Percent
Protein Identity:
100
55.2
46
83.4
N.A.
80.1
80
N.A.
N.A.
73.4
N.A.
66.6
N.A.
40.9
47.9
33.5
45.8
Protein Similarity:
100
66.8
46.7
89.6
N.A.
87.1
86.8
N.A.
N.A.
83.5
N.A.
79.3
N.A.
60
65.4
49.8
61.8
P-Site Identity:
100
13.3
13.3
86.6
N.A.
86.6
86.6
N.A.
N.A.
80
N.A.
20
N.A.
6.6
0
6.6
20
P-Site Similarity:
100
20
26.6
86.6
N.A.
86.6
86.6
N.A.
N.A.
86.6
N.A.
20
N.A.
26.6
0
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
54
24
16
0
0
0
0
0
8
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% C
% Asp:
0
0
0
8
54
47
16
16
39
16
8
16
0
24
0
% D
% Glu:
0
0
0
0
8
8
47
16
16
16
16
8
47
16
54
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
16
0
0
0
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
8
0
0
0
0
8
8
0
8
8
0
0
8
0
0
% L
% Met:
0
8
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
24
0
0
8
8
8
0
0
0
0
0
0
0
0
8
% P
% Gln:
8
8
0
0
0
0
0
0
0
8
39
8
0
0
0
% Q
% Arg:
0
8
0
8
0
0
0
8
0
0
0
8
8
0
0
% R
% Ser:
8
0
8
8
8
16
8
47
8
8
0
8
8
0
8
% S
% Thr:
0
8
16
0
0
8
0
0
0
0
8
39
8
0
16
% T
% Val:
31
8
24
47
16
0
16
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
8
0
0
8
39
16
0
8
39
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _