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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA7
All Species:
1.82
Human Site:
S1294
Identified Species:
3.33
UniProt:
Q6ZV29
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZV29
NP_001092007.1
1317
145733
S1294
G
S
D
L
E
D
E
S
S
L
R
H
R
H
P
Chimpanzee
Pan troglodytes
XP_512331
1484
162976
T1456
P
E
G
A
S
P
S
T
A
S
E
M
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001117679
626
69102
L604
S
D
S
E
D
E
S
L
L
Q
H
G
H
P
S
Dog
Lupus familis
XP_537782
1344
148918
P1319
G
S
D
S
E
D
E
P
S
F
R
H
R
R
P
Cat
Felis silvestris
Mouse
Mus musculus
A2AJ88
1352
150476
P1316
D
S
D
S
E
Y
E
P
S
M
L
Q
G
P
P
Rat
Rattus norvegicus
Q5BK26
1349
150006
P1313
D
S
D
S
E
C
E
P
S
M
S
Q
G
P
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124214
1324
147712
V1302
D
S
D
S
D
E
D
V
Q
I
R
K
R
K
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692276
1315
147148
E1285
Q
E
D
E
D
E
E
E
E
T
A
D
T
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U969
1425
160554
T1318
N
S
L
S
F
S
E
T
E
M
D
S
D
V
E
Honey Bee
Apis mellifera
XP_001120383
1324
149002
D1290
E
P
T
A
G
I
L
D
Q
S
P
D
E
N
R
Nematode Worm
Caenorhab. elegans
Q02331
1353
152377
E1308
D
T
D
Y
Y
E
E
E
S
S
Q
S
E
N
G
Sea Urchin
Strong. purpuratus
XP_001202094
1454
161991
P1387
M
N
P
S
S
D
V
P
N
A
T
N
S
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S8J1
1515
167542
G1475
F
D
E
I
Y
G
V
G
Y
K
Y
G
Q
E
F
Conservation
Percent
Protein Identity:
100
55.2
46
83.4
N.A.
80.1
80
N.A.
N.A.
73.4
N.A.
66.6
N.A.
40.9
47.9
33.5
45.8
Protein Similarity:
100
66.8
46.7
89.6
N.A.
87.1
86.8
N.A.
N.A.
83.5
N.A.
79.3
N.A.
60
65.4
49.8
61.8
P-Site Identity:
100
0
0
73.3
N.A.
40
33.3
N.A.
N.A.
26.6
N.A.
13.3
N.A.
13.3
0
20
6.6
P-Site Similarity:
100
13.3
13.3
73.3
N.A.
46.6
40
N.A.
N.A.
53.3
N.A.
26.6
N.A.
26.6
6.6
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
0
0
0
8
8
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
31
16
54
0
24
24
8
8
0
0
8
16
8
0
8
% D
% Glu:
8
16
8
16
31
31
54
16
16
0
8
0
24
24
16
% E
% Phe:
8
0
0
0
8
0
0
0
0
8
0
0
0
0
8
% F
% Gly:
16
0
8
0
8
8
0
8
0
0
0
16
16
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
16
8
8
8
% H
% Ile:
0
0
0
8
0
8
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% K
% Leu:
0
0
8
8
0
0
8
8
8
8
8
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
24
0
8
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
8
0
0
8
0
16
8
% N
% Pro:
8
8
8
0
0
8
0
31
0
0
8
0
0
24
24
% P
% Gln:
8
0
0
0
0
0
0
0
16
8
8
16
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
24
0
24
8
8
% R
% Ser:
8
47
8
47
16
8
16
8
39
24
8
16
8
0
8
% S
% Thr:
0
8
8
0
0
0
0
16
0
8
8
0
8
0
8
% T
% Val:
0
0
0
0
0
0
16
8
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
16
8
0
0
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _