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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA7
All Species:
23.94
Human Site:
S181
Identified Species:
43.89
UniProt:
Q6ZV29
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZV29
NP_001092007.1
1317
145733
S181
Q
P
R
E
P
D
P
S
I
C
V
V
Q
D
G
Chimpanzee
Pan troglodytes
XP_512331
1484
162976
S340
R
P
G
Q
P
D
A
S
I
Y
V
V
Q
D
G
Rhesus Macaque
Macaca mulatta
XP_001117679
626
69102
Dog
Lupus familis
XP_537782
1344
148918
S206
Q
P
G
E
P
D
T
S
I
Y
V
V
Q
D
G
Cat
Felis silvestris
Mouse
Mus musculus
A2AJ88
1352
150476
S206
Q
P
G
E
P
D
I
S
I
Y
V
V
Q
D
G
Rat
Rattus norvegicus
Q5BK26
1349
150006
S206
Q
P
G
E
P
D
I
S
I
Y
V
V
Q
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124214
1324
147712
S201
R
P
G
Q
L
D
N
S
I
Y
V
V
Q
D
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692276
1315
147148
C158
K
P
L
F
L
E
L
C
R
H
M
V
F
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U969
1425
160554
S210
K
I
T
D
P
D
D
S
V
Y
I
V
Q
S
G
Honey Bee
Apis mellifera
XP_001120383
1324
149002
E185
L
K
L
C
K
H
T
E
I
M
N
L
P
A
G
Nematode Worm
Caenorhab. elegans
Q02331
1353
152377
A160
E
S
S
D
E
E
N
A
N
V
V
M
G
G
G
Sea Urchin
Strong. purpuratus
XP_001202094
1454
161991
S103
Q
R
G
Q
P
D
D
S
I
F
V
V
Q
C
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S8J1
1515
167542
G207
L
N
L
E
E
E
Q
G
F
C
L
V
V
D
G
Conservation
Percent
Protein Identity:
100
55.2
46
83.4
N.A.
80.1
80
N.A.
N.A.
73.4
N.A.
66.6
N.A.
40.9
47.9
33.5
45.8
Protein Similarity:
100
66.8
46.7
89.6
N.A.
87.1
86.8
N.A.
N.A.
83.5
N.A.
79.3
N.A.
60
65.4
49.8
61.8
P-Site Identity:
100
66.6
0
80
N.A.
80
80
N.A.
N.A.
60
N.A.
13.3
N.A.
40
13.3
13.3
60
P-Site Similarity:
100
80
0
80
N.A.
80
80
N.A.
N.A.
73.3
N.A.
33.3
N.A.
66.6
20
46.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
8
0
0
0
8
0
16
0
0
0
8
0
% C
% Asp:
0
0
0
16
0
62
16
0
0
0
0
0
0
54
0
% D
% Glu:
8
0
0
39
16
24
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
8
8
0
0
8
0
0
% F
% Gly:
0
0
47
0
0
0
0
8
0
0
0
0
8
8
85
% G
% His:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
16
0
62
0
8
0
0
0
0
% I
% Lys:
16
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
16
0
24
0
16
0
8
0
0
0
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
8
8
0
0
0
% M
% Asn:
0
8
0
0
0
0
16
0
8
0
8
0
0
0
0
% N
% Pro:
0
54
0
0
54
0
8
0
0
0
0
0
8
0
0
% P
% Gln:
39
0
0
24
0
0
8
0
0
0
0
0
62
0
8
% Q
% Arg:
16
8
8
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
8
8
0
0
0
0
62
0
0
0
0
0
8
0
% S
% Thr:
0
0
8
0
0
0
16
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
8
62
77
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
47
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _