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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA7
All Species:
10.91
Human Site:
S353
Identified Species:
20
UniProt:
Q6ZV29
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZV29
NP_001092007.1
1317
145733
S353
A
G
P
L
L
K
R
S
H
S
V
P
A
P
S
Chimpanzee
Pan troglodytes
XP_512331
1484
162976
S515
G
D
P
V
K
P
T
S
L
E
T
P
S
A
P
Rhesus Macaque
Macaca mulatta
XP_001117679
626
69102
Dog
Lupus familis
XP_537782
1344
148918
S378
S
G
P
L
L
K
R
S
Q
S
S
P
L
P
S
Cat
Felis silvestris
Mouse
Mus musculus
A2AJ88
1352
150476
S377
S
G
P
L
L
K
R
S
C
S
V
P
L
P
S
Rat
Rattus norvegicus
Q5BK26
1349
150006
C376
G
P
L
L
K
R
S
C
S
V
P
L
P
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124214
1324
147712
G369
M
D
T
L
K
N
S
G
T
E
N
P
E
H
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692276
1315
147148
S343
S
D
H
Y
S
D
T
S
H
M
S
R
E
D
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U969
1425
160554
P381
V
S
V
T
V
T
R
P
P
S
S
P
S
R
H
Honey Bee
Apis mellifera
XP_001120383
1324
149002
F352
I
E
N
Q
S
N
T
F
T
T
I
S
S
E
H
Nematode Worm
Caenorhab. elegans
Q02331
1353
152377
Y355
I
T
S
F
R
E
S
Y
H
K
N
P
E
A
W
Sea Urchin
Strong. purpuratus
XP_001202094
1454
161991
A435
S
A
L
S
T
S
S
A
E
T
V
L
R
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S8J1
1515
167542
E505
S
A
A
S
L
R
K
E
V
A
L
Q
A
Y
S
Conservation
Percent
Protein Identity:
100
55.2
46
83.4
N.A.
80.1
80
N.A.
N.A.
73.4
N.A.
66.6
N.A.
40.9
47.9
33.5
45.8
Protein Similarity:
100
66.8
46.7
89.6
N.A.
87.1
86.8
N.A.
N.A.
83.5
N.A.
79.3
N.A.
60
65.4
49.8
61.8
P-Site Identity:
100
20
0
73.3
N.A.
80
13.3
N.A.
N.A.
13.3
N.A.
13.3
N.A.
20
0
13.3
13.3
P-Site Similarity:
100
33.3
0
80
N.A.
86.6
20
N.A.
N.A.
13.3
N.A.
20
N.A.
33.3
20
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
8
0
0
0
0
8
0
8
0
0
16
16
0
% A
% Cys:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
8
% C
% Asp:
0
24
0
0
0
8
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
8
0
0
0
8
0
8
8
16
0
0
24
8
0
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
16
24
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
24
0
0
0
0
8
16
% H
% Ile:
16
0
0
0
0
0
0
0
0
0
8
0
0
0
16
% I
% Lys:
0
0
0
0
24
24
8
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
16
39
31
0
0
0
8
0
8
16
16
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
16
0
0
0
0
16
0
0
0
0
% N
% Pro:
0
8
31
0
0
8
0
8
8
0
8
54
8
31
8
% P
% Gln:
0
0
0
8
0
0
0
0
8
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
8
16
31
0
0
0
0
8
8
8
0
% R
% Ser:
39
8
8
16
16
8
31
39
8
31
24
8
24
0
39
% S
% Thr:
0
8
8
8
8
8
24
0
16
16
8
0
0
0
0
% T
% Val:
8
0
8
8
8
0
0
0
8
8
24
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
8
0
0
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _