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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA7
All Species:
5.45
Human Site:
S416
Identified Species:
10
UniProt:
Q6ZV29
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZV29
NP_001092007.1
1317
145733
S416
H
P
G
S
S
V
A
S
K
S
R
K
S
V
M
Chimpanzee
Pan troglodytes
XP_512331
1484
162976
P578
A
R
T
P
T
Q
E
P
R
E
Q
P
A
G
A
Rhesus Macaque
Macaca mulatta
XP_001117679
626
69102
Dog
Lupus familis
XP_537782
1344
148918
S441
H
P
G
S
T
M
A
S
K
S
K
K
N
V
M
Cat
Felis silvestris
Mouse
Mus musculus
A2AJ88
1352
150476
A438
E
Q
L
G
N
S
L
A
S
K
S
K
K
S
V
Rat
Rattus norvegicus
Q5BK26
1349
150006
L435
E
E
Q
L
G
S
S
L
A
S
K
S
K
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124214
1324
147712
L427
P
V
V
G
K
S
I
L
K
K
T
V
T
V
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692276
1315
147148
N405
P
I
A
I
Q
K
S
N
R
K
K
S
V
T
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U969
1425
160554
I445
L
S
T
R
R
S
S
I
T
L
M
A
P
D
G
Honey Bee
Apis mellifera
XP_001120383
1324
149002
Q414
I
T
S
Q
Q
G
S
Q
P
D
V
I
H
T
G
Nematode Worm
Caenorhab. elegans
Q02331
1353
152377
K417
L
Q
L
S
L
S
L
K
K
K
E
K
P
F
N
Sea Urchin
Strong. purpuratus
XP_001202094
1454
161991
A511
Q
I
S
L
E
N
A
A
A
A
S
S
K
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S8J1
1515
167542
S565
D
L
A
R
D
A
T
S
P
R
P
Q
R
N
L
Conservation
Percent
Protein Identity:
100
55.2
46
83.4
N.A.
80.1
80
N.A.
N.A.
73.4
N.A.
66.6
N.A.
40.9
47.9
33.5
45.8
Protein Similarity:
100
66.8
46.7
89.6
N.A.
87.1
86.8
N.A.
N.A.
83.5
N.A.
79.3
N.A.
60
65.4
49.8
61.8
P-Site Identity:
100
0
0
73.3
N.A.
6.6
6.6
N.A.
N.A.
13.3
N.A.
6.6
N.A.
0
0
20
6.6
P-Site Similarity:
100
26.6
0
100
N.A.
26.6
20
N.A.
N.A.
20
N.A.
33.3
N.A.
6.6
6.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
0
0
8
24
16
16
8
0
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
0
0
8
0
0
0
8
0
% D
% Glu:
16
8
0
0
8
0
8
0
0
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
16
16
8
8
0
0
0
0
0
0
0
8
24
% G
% His:
16
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
16
0
8
0
0
8
8
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
8
8
0
8
31
31
24
31
24
8
0
% K
% Leu:
16
8
16
16
8
0
16
16
0
8
0
0
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
24
% M
% Asn:
0
0
0
0
8
8
0
8
0
0
0
0
8
8
8
% N
% Pro:
16
16
0
8
0
0
0
8
16
0
8
8
16
0
0
% P
% Gln:
8
16
8
8
16
8
0
8
0
0
8
8
0
0
0
% Q
% Arg:
0
8
0
16
8
0
0
0
16
8
8
0
8
0
0
% R
% Ser:
0
8
16
24
8
39
31
24
8
24
16
24
8
16
8
% S
% Thr:
0
8
16
0
16
0
8
0
8
0
8
0
8
16
8
% T
% Val:
0
8
8
0
0
8
0
0
0
0
8
8
8
24
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _