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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA7
All Species:
7.88
Human Site:
S445
Identified Species:
14.44
UniProt:
Q6ZV29
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZV29
NP_001092007.1
1317
145733
S445
H
T
D
E
T
L
A
S
R
K
S
D
A
I
F
Chimpanzee
Pan troglodytes
XP_512331
1484
162976
G607
C
P
F
G
P
Y
Q
G
R
Q
T
S
S
I
F
Rhesus Macaque
Macaca mulatta
XP_001117679
626
69102
Dog
Lupus familis
XP_537782
1344
148918
S470
N
S
E
E
T
V
S
S
R
K
T
D
A
I
F
Cat
Felis silvestris
Mouse
Mus musculus
A2AJ88
1352
150476
C467
F
R
D
E
T
G
A
C
G
K
T
D
A
I
F
Rat
Rattus norvegicus
Q5BK26
1349
150006
S464
P
R
D
E
P
G
P
S
G
R
T
D
A
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124214
1324
147712
G456
T
A
Q
E
S
C
N
G
K
P
T
D
A
I
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692276
1315
147148
H434
G
H
S
S
H
I
H
H
S
K
V
N
A
I
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U969
1425
160554
S474
D
M
R
L
V
Q
S
S
A
V
D
S
L
R
K
Honey Bee
Apis mellifera
XP_001120383
1324
149002
H443
Q
Q
Q
L
D
E
A
H
L
V
Q
I
A
T
E
Nematode Worm
Caenorhab. elegans
Q02331
1353
152377
L446
W
M
A
E
A
F
G
L
V
A
D
D
V
V
S
Sea Urchin
Strong. purpuratus
XP_001202094
1454
161991
D540
R
S
S
E
E
K
K
D
Y
S
E
D
E
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S8J1
1515
167542
D594
T
R
E
A
L
D
E
D
D
M
F
R
E
S
V
Conservation
Percent
Protein Identity:
100
55.2
46
83.4
N.A.
80.1
80
N.A.
N.A.
73.4
N.A.
66.6
N.A.
40.9
47.9
33.5
45.8
Protein Similarity:
100
66.8
46.7
89.6
N.A.
87.1
86.8
N.A.
N.A.
83.5
N.A.
79.3
N.A.
60
65.4
49.8
61.8
P-Site Identity:
100
20
0
60
N.A.
60
46.6
N.A.
N.A.
33.3
N.A.
26.6
N.A.
6.6
13.3
13.3
20
P-Site Similarity:
100
40
0
100
N.A.
66.6
60
N.A.
N.A.
53.3
N.A.
40
N.A.
13.3
13.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
8
0
24
0
8
8
0
0
54
0
0
% A
% Cys:
8
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
24
0
8
8
0
16
8
0
16
54
0
0
0
% D
% Glu:
0
0
16
54
8
8
8
0
0
0
8
0
16
0
8
% E
% Phe:
8
0
8
0
0
8
0
0
0
0
8
0
0
0
54
% F
% Gly:
8
0
0
8
0
16
8
16
16
0
0
0
0
0
0
% G
% His:
8
8
0
0
8
0
8
16
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
8
0
62
0
% I
% Lys:
0
0
0
0
0
8
8
0
8
31
0
0
0
0
8
% K
% Leu:
0
0
0
16
8
8
0
8
8
0
0
0
8
0
8
% L
% Met:
0
16
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% N
% Pro:
8
8
0
0
16
0
8
0
0
8
0
0
0
0
0
% P
% Gln:
8
8
16
0
0
8
8
0
0
8
8
0
0
0
0
% Q
% Arg:
8
24
8
0
0
0
0
0
24
8
0
8
0
8
0
% R
% Ser:
0
16
16
8
8
0
16
31
8
8
8
16
8
8
8
% S
% Thr:
16
8
0
0
24
0
0
0
0
0
39
0
0
8
0
% T
% Val:
0
0
0
0
8
8
0
0
8
16
8
0
8
8
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _