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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA7
All Species:
17.27
Human Site:
S718
Identified Species:
31.67
UniProt:
Q6ZV29
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZV29
NP_001092007.1
1317
145733
S718
L
G
L
P
T
E
G
S
K
W
D
L
G
N
P
Chimpanzee
Pan troglodytes
XP_512331
1484
162976
P880
G
G
V
G
V
G
C
P
G
V
R
A
C
W
G
Rhesus Macaque
Macaca mulatta
XP_001117679
626
69102
G67
E
H
A
L
S
A
I
G
P
T
L
L
L
T
S
Dog
Lupus familis
XP_537782
1344
148918
S743
F
G
L
H
T
A
G
S
K
W
D
T
G
N
P
Cat
Felis silvestris
Mouse
Mus musculus
A2AJ88
1352
150476
S740
L
G
F
N
T
A
S
S
K
W
D
L
G
N
P
Rat
Rattus norvegicus
Q5BK26
1349
150006
S737
L
G
F
N
T
A
S
S
K
W
D
L
G
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124214
1324
147712
S726
F
G
L
H
S
P
S
S
K
W
D
A
G
N
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692276
1315
147148
S709
L
G
F
H
S
P
T
S
K
W
D
A
G
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U969
1425
160554
P747
G
A
P
V
E
A
N
P
V
T
H
K
Y
S
T
Honey Bee
Apis mellifera
XP_001120383
1324
149002
D716
N
G
A
A
A
T
V
D
A
R
P
A
Q
V
N
Nematode Worm
Caenorhab. elegans
Q02331
1353
152377
G714
V
I
R
T
N
E
L
G
A
T
D
P
M
S
H
Sea Urchin
Strong. purpuratus
XP_001202094
1454
161991
T813
T
G
K
W
V
Y
Q
T
T
V
E
N
L
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S8J1
1515
167542
V861
V
Q
V
N
S
G
Q
V
L
F
R
E
G
D
E
Conservation
Percent
Protein Identity:
100
55.2
46
83.4
N.A.
80.1
80
N.A.
N.A.
73.4
N.A.
66.6
N.A.
40.9
47.9
33.5
45.8
Protein Similarity:
100
66.8
46.7
89.6
N.A.
87.1
86.8
N.A.
N.A.
83.5
N.A.
79.3
N.A.
60
65.4
49.8
61.8
P-Site Identity:
100
6.6
6.6
73.3
N.A.
73.3
73.3
N.A.
N.A.
60
N.A.
60
N.A.
0
6.6
13.3
6.6
P-Site Similarity:
100
13.3
13.3
73.3
N.A.
73.3
73.3
N.A.
N.A.
66.6
N.A.
66.6
N.A.
6.6
6.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
8
8
39
0
0
16
0
0
31
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
54
0
0
8
0
% D
% Glu:
8
0
0
0
8
16
0
0
0
0
8
8
0
0
8
% E
% Phe:
16
0
24
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
16
70
0
8
0
16
16
16
8
0
0
0
54
0
8
% G
% His:
0
8
0
24
0
0
0
0
0
0
8
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
47
0
0
8
0
0
0
% K
% Leu:
31
0
24
8
0
0
8
0
8
0
8
31
16
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
0
0
24
8
0
8
0
0
0
0
8
0
47
8
% N
% Pro:
0
0
8
8
0
16
0
16
8
0
8
8
0
0
47
% P
% Gln:
0
8
0
0
0
0
16
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
8
16
0
0
0
0
% R
% Ser:
0
0
0
0
31
0
24
47
0
0
0
0
0
24
8
% S
% Thr:
8
0
0
8
31
8
8
8
8
24
0
8
0
8
16
% T
% Val:
16
0
16
8
16
0
8
8
8
16
0
0
0
8
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
47
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _