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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA7
All Species:
19.7
Human Site:
T517
Identified Species:
36.11
UniProt:
Q6ZV29
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZV29
NP_001092007.1
1317
145733
T517
K
I
G
S
Q
E
D
T
C
L
F
L
T
R
P
Chimpanzee
Pan troglodytes
XP_512331
1484
162976
V679
M
I
D
K
A
E
D
V
C
L
F
V
A
Q
P
Rhesus Macaque
Macaca mulatta
XP_001117679
626
69102
Dog
Lupus familis
XP_537782
1344
148918
T542
K
I
D
S
E
E
D
T
C
L
F
V
V
R
P
Cat
Felis silvestris
Mouse
Mus musculus
A2AJ88
1352
150476
T539
K
I
D
S
L
E
D
T
C
L
F
L
T
H
P
Rat
Rattus norvegicus
Q5BK26
1349
150006
T536
K
I
D
S
L
E
D
T
C
L
F
L
T
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124214
1324
147712
T528
K
V
D
S
E
E
D
T
C
L
F
I
T
H
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692276
1315
147148
S506
L
I
D
R
E
E
Q
S
C
L
F
V
A
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U969
1425
160554
M546
A
K
Q
D
K
S
D
M
L
I
H
F
V
H
P
Honey Bee
Apis mellifera
XP_001120383
1324
149002
V515
G
R
D
V
G
Q
E
V
H
M
F
S
A
H
Q
Nematode Worm
Caenorhab. elegans
Q02331
1353
152377
S518
E
N
N
E
E
D
E
S
A
V
I
R
V
T
A
Sea Urchin
Strong. purpuratus
XP_001202094
1454
161991
R612
D
E
I
S
G
K
E
R
T
V
F
V
V
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S8J1
1515
167542
F666
E
S
V
T
S
C
G
F
S
S
S
S
P
V
P
Conservation
Percent
Protein Identity:
100
55.2
46
83.4
N.A.
80.1
80
N.A.
N.A.
73.4
N.A.
66.6
N.A.
40.9
47.9
33.5
45.8
Protein Similarity:
100
66.8
46.7
89.6
N.A.
87.1
86.8
N.A.
N.A.
83.5
N.A.
79.3
N.A.
60
65.4
49.8
61.8
P-Site Identity:
100
46.6
0
73.3
N.A.
80
80
N.A.
N.A.
66.6
N.A.
40
N.A.
13.3
6.6
0
13.3
P-Site Similarity:
100
60
0
86.6
N.A.
80
80
N.A.
N.A.
86.6
N.A.
60
N.A.
26.6
26.6
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
0
8
0
0
0
24
0
8
% A
% Cys:
0
0
0
0
0
8
0
0
54
0
0
0
0
0
0
% C
% Asp:
8
0
54
8
0
8
54
0
0
0
0
0
0
0
0
% D
% Glu:
16
8
0
8
31
54
24
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
70
8
0
0
0
% F
% Gly:
8
0
8
0
16
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
8
0
0
47
8
% H
% Ile:
0
47
8
0
0
0
0
0
0
8
8
8
0
0
0
% I
% Lys:
39
8
0
8
8
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
16
0
0
0
8
54
0
24
0
0
0
% L
% Met:
8
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
70
% P
% Gln:
0
0
8
0
8
8
8
0
0
0
0
0
0
8
8
% Q
% Arg:
0
8
0
8
0
0
0
8
0
0
0
8
0
16
0
% R
% Ser:
0
8
0
47
8
8
0
16
8
8
8
16
0
8
0
% S
% Thr:
0
0
0
8
0
0
0
39
8
0
0
0
31
8
0
% T
% Val:
0
8
8
8
0
0
0
16
0
16
0
31
31
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _