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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA7
All Species:
16.06
Human Site:
Y1264
Identified Species:
29.44
UniProt:
Q6ZV29
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZV29
NP_001092007.1
1317
145733
Y1264
E
S
D
Y
Q
T
E
Y
E
E
E
L
L
D
V
Chimpanzee
Pan troglodytes
XP_512331
1484
162976
E1426
D
G
C
A
D
G
E
E
S
D
C
L
T
E
Y
Rhesus Macaque
Macaca mulatta
XP_001117679
626
69102
E574
S
D
Y
Q
T
E
Y
E
E
E
L
L
D
V
P
Dog
Lupus familis
XP_537782
1344
148918
Y1289
E
S
D
Y
Q
T
E
Y
E
E
E
L
P
D
G
Cat
Felis silvestris
Mouse
Mus musculus
A2AJ88
1352
150476
Y1286
E
S
D
Y
Q
T
E
Y
E
E
E
L
P
A
I
Rat
Rattus norvegicus
Q5BK26
1349
150006
Y1283
E
S
D
Y
Q
T
E
Y
E
E
E
L
P
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124214
1324
147712
Y1272
E
S
D
Y
Q
T
E
Y
E
E
E
V
L
D
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692276
1315
147148
D1255
E
E
S
E
Y
Q
T
D
Y
D
E
D
A
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U969
1425
160554
D1288
F
S
E
D
E
D
C
D
G
Y
I
S
E
P
T
Honey Bee
Apis mellifera
XP_001120383
1324
149002
D1260
V
D
L
E
I
D
S
D
T
D
E
L
E
E
Y
Nematode Worm
Caenorhab. elegans
Q02331
1353
152377
N1278
L
R
H
S
M
S
L
N
P
S
A
N
G
P
V
Sea Urchin
Strong. purpuratus
XP_001202094
1454
161991
V1357
D
E
V
D
Y
A
R
V
E
G
T
G
D
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S8J1
1515
167542
K1445
V
G
E
L
E
R
A
K
T
M
P
G
C
I
Y
Conservation
Percent
Protein Identity:
100
55.2
46
83.4
N.A.
80.1
80
N.A.
N.A.
73.4
N.A.
66.6
N.A.
40.9
47.9
33.5
45.8
Protein Similarity:
100
66.8
46.7
89.6
N.A.
87.1
86.8
N.A.
N.A.
83.5
N.A.
79.3
N.A.
60
65.4
49.8
61.8
P-Site Identity:
100
13.3
20
86.6
N.A.
80
80
N.A.
N.A.
86.6
N.A.
13.3
N.A.
6.6
13.3
6.6
6.6
P-Site Similarity:
100
33.3
20
86.6
N.A.
86.6
86.6
N.A.
N.A.
93.3
N.A.
26.6
N.A.
20
26.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
8
0
0
0
8
0
8
16
0
% A
% Cys:
0
0
8
0
0
0
8
0
0
0
8
0
8
0
0
% C
% Asp:
16
16
39
16
8
16
0
24
0
24
0
8
16
24
8
% D
% Glu:
47
16
16
16
16
8
47
16
54
47
54
0
16
16
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
16
0
0
0
8
0
0
8
8
0
16
8
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
8
0
0
8
16
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
8
0
8
8
0
0
8
0
0
0
8
54
16
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
8
0
24
16
8
% P
% Gln:
0
0
0
8
39
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
8
8
0
0
0
0
0
0
0
0
% R
% Ser:
8
47
8
8
0
8
8
0
8
8
0
8
0
0
0
% S
% Thr:
0
0
0
0
8
39
8
0
16
0
8
0
8
8
8
% T
% Val:
16
0
8
0
0
0
0
8
0
0
0
8
0
16
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
39
16
0
8
39
8
8
0
0
0
0
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _