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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA7
All Species:
22.42
Human Site:
Y258
Identified Species:
41.11
UniProt:
Q6ZV29
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZV29
NP_001092007.1
1317
145733
Y258
F
H
G
V
F
E
K
Y
P
E
T
L
V
R
V
Chimpanzee
Pan troglodytes
XP_512331
1484
162976
Y417
F
S
A
V
F
T
K
Y
P
E
S
L
V
R
V
Rhesus Macaque
Macaca mulatta
XP_001117679
626
69102
Dog
Lupus familis
XP_537782
1344
148918
Y283
F
Q
G
V
F
E
K
Y
P
E
T
L
V
R
V
Cat
Felis silvestris
Mouse
Mus musculus
A2AJ88
1352
150476
Y283
F
Q
G
V
F
E
K
Y
P
E
T
L
V
R
V
Rat
Rattus norvegicus
Q5BK26
1349
150006
Y283
F
Q
G
V
F
E
K
Y
P
E
T
L
V
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124214
1324
147712
K277
A
F
Q
D
V
F
Q
K
Y
P
E
T
L
V
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692276
1315
147148
A250
V
L
R
L
P
A
Q
A
F
Q
S
V
F
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U969
1425
160554
N287
F
E
E
V
F
Q
D
N
P
D
V
M
I
R
V
Honey Bee
Apis mellifera
XP_001120383
1324
149002
A260
Y
K
T
V
S
A
R
A
V
E
D
S
I
V
V
Nematode Worm
Caenorhab. elegans
Q02331
1353
152377
P251
N
L
K
M
L
E
L
P
S
E
W
K
L
D
P
Sea Urchin
Strong. purpuratus
XP_001202094
1454
161991
Y340
F
Q
A
V
F
E
Q
Y
P
E
S
M
V
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S8J1
1515
167542
Y405
F
R
R
L
I
K
I
Y
P
K
A
T
A
H
I
Conservation
Percent
Protein Identity:
100
55.2
46
83.4
N.A.
80.1
80
N.A.
N.A.
73.4
N.A.
66.6
N.A.
40.9
47.9
33.5
45.8
Protein Similarity:
100
66.8
46.7
89.6
N.A.
87.1
86.8
N.A.
N.A.
83.5
N.A.
79.3
N.A.
60
65.4
49.8
61.8
P-Site Identity:
100
73.3
0
93.3
N.A.
93.3
93.3
N.A.
N.A.
0
N.A.
0
N.A.
40
20
13.3
66.6
P-Site Similarity:
100
80
0
93.3
N.A.
93.3
93.3
N.A.
N.A.
13.3
N.A.
33.3
N.A.
66.6
40
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
0
0
16
0
16
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
8
8
0
0
16
0
% D
% Glu:
0
8
8
0
0
47
0
0
0
62
8
0
0
0
0
% E
% Phe:
62
8
0
0
54
8
0
0
8
0
0
0
8
0
0
% F
% Gly:
0
0
31
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
8
0
8
0
0
0
0
0
16
0
8
% I
% Lys:
0
8
8
0
0
8
39
8
0
8
0
8
0
0
8
% K
% Leu:
0
16
0
16
8
0
8
0
0
0
0
39
16
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
16
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
8
62
8
0
0
0
0
8
% P
% Gln:
0
31
8
0
0
8
24
0
0
8
0
0
0
0
0
% Q
% Arg:
0
8
16
0
0
0
8
0
0
0
0
0
0
54
8
% R
% Ser:
0
8
0
0
8
0
0
0
8
0
24
8
0
0
0
% S
% Thr:
0
0
8
0
0
8
0
0
0
0
31
16
0
0
0
% T
% Val:
8
0
0
62
8
0
0
0
8
0
8
8
47
16
62
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
54
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _