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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA7
All Species:
30
Human Site:
Y682
Identified Species:
55
UniProt:
Q6ZV29
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZV29
NP_001092007.1
1317
145733
Y682
L
T
S
I
K
R
R
Y
P
Q
V
V
T
R
L
Chimpanzee
Pan troglodytes
XP_512331
1484
162976
Y844
L
G
H
I
K
R
R
Y
P
Q
V
V
T
R
L
Rhesus Macaque
Macaca mulatta
XP_001117679
626
69102
S31
T
A
G
S
K
W
D
S
G
N
P
A
V
N
L
Dog
Lupus familis
XP_537782
1344
148918
Y707
L
T
S
I
K
R
R
Y
P
Q
V
V
T
R
L
Cat
Felis silvestris
Mouse
Mus musculus
A2AJ88
1352
150476
Y704
L
T
S
I
K
R
R
Y
P
Q
V
V
T
R
L
Rat
Rattus norvegicus
Q5BK26
1349
150006
Y701
L
T
S
I
K
R
R
Y
P
Q
V
V
T
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124214
1324
147712
K690
E
G
A
L
T
S
I
K
R
K
F
P
Q
V
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692276
1315
147148
Q673
S
I
K
R
K
Y
P
Q
V
V
T
R
L
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U969
1425
160554
Y711
F
N
A
I
K
L
R
Y
P
I
V
V
T
K
L
Honey Bee
Apis mellifera
XP_001120383
1324
149002
Y680
F
N
V
I
K
L
R
Y
P
I
V
V
T
R
L
Nematode Worm
Caenorhab. elegans
Q02331
1353
152377
Y678
L
N
F
I
K
M
Q
Y
P
Q
V
G
F
R
L
Sea Urchin
Strong. purpuratus
XP_001202094
1454
161991
F777
L
N
L
I
K
R
K
F
P
H
T
V
T
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S8J1
1515
167542
Y825
I
D
R
I
V
D
R
Y
P
I
V
M
L
T
M
Conservation
Percent
Protein Identity:
100
55.2
46
83.4
N.A.
80.1
80
N.A.
N.A.
73.4
N.A.
66.6
N.A.
40.9
47.9
33.5
45.8
Protein Similarity:
100
66.8
46.7
89.6
N.A.
87.1
86.8
N.A.
N.A.
83.5
N.A.
79.3
N.A.
60
65.4
49.8
61.8
P-Site Identity:
100
86.6
13.3
100
N.A.
100
100
N.A.
N.A.
0
N.A.
6.6
N.A.
60
66.6
60
60
P-Site Similarity:
100
86.6
13.3
100
N.A.
100
100
N.A.
N.A.
26.6
N.A.
6.6
N.A.
73.3
66.6
66.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
0
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
8
8
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
16
0
8
0
0
0
0
8
0
0
8
0
8
0
0
% F
% Gly:
0
16
8
0
0
0
0
0
8
0
0
8
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
8
% H
% Ile:
8
8
0
77
0
0
8
0
0
24
0
0
0
8
0
% I
% Lys:
0
0
8
0
85
0
8
8
0
8
0
0
0
8
0
% K
% Leu:
54
0
8
8
0
16
0
0
0
0
0
0
16
0
77
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
31
0
0
0
0
0
0
0
8
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
8
0
77
0
8
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
8
0
47
0
0
8
0
0
% Q
% Arg:
0
0
8
8
0
47
62
0
8
0
0
8
0
62
0
% R
% Ser:
8
0
31
8
0
8
0
8
0
0
0
0
0
0
0
% S
% Thr:
8
31
0
0
8
0
0
0
0
0
16
0
62
8
0
% T
% Val:
0
0
8
0
8
0
0
0
8
8
70
62
8
8
8
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _