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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGD6 All Species: 19.7
Human Site: S349 Identified Species: 54.17
UniProt: Q6ZV73 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZV73 NP_060821.3 1430 160816 S349 G N S D S S S S C L T E N S L
Chimpanzee Pan troglodytes XP_001142099 1430 160830 S349 G N S D S S S S C L T E N S L
Rhesus Macaque Macaca mulatta XP_001106559 1431 160939 S349 G N S D S S S S C L T E N S L
Dog Lupus familis XP_854794 1471 164544 S405 G N L D S N S S C L L D A A L
Cat Felis silvestris
Mouse Mus musculus Q69ZL1 1399 155151 T330 V D T P G E S T E E P G N S N
Rat Rattus norvegicus NP_001131117 1406 157019 S339 E S S N N G S S C L H E D S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510070 1533 171433 F470 S A S D S F S F A E H C M K K
Chicken Gallus gallus XP_416149 1453 162099 F370 S S S E N D S F G P A E H S F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001093450 1315 147421 S305 I E N T D T D S S T K S D P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 96.6 83.6 N.A. 74.3 75 N.A. 59.5 62.2 N.A. 41.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 98.6 88.1 N.A. 82 83.1 N.A. 70.1 74.8 N.A. 58.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 60 N.A. 20 53.3 N.A. 26.6 26.6 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 40 80 N.A. 26.6 53.3 N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 0 0 12 0 12 0 12 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 56 0 0 12 0 0 0 % C
% Asp: 0 12 0 56 12 12 12 0 0 0 0 12 23 0 0 % D
% Glu: 12 12 0 12 0 12 0 0 12 23 0 56 0 0 0 % E
% Phe: 0 0 0 0 0 12 0 23 0 0 0 0 0 0 12 % F
% Gly: 45 0 0 0 12 12 0 0 12 0 0 12 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 23 0 12 0 0 % H
% Ile: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 12 0 0 12 12 % K
% Leu: 0 0 12 0 0 0 0 0 0 56 12 0 0 0 67 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % M
% Asn: 0 45 12 12 23 12 0 0 0 0 0 0 45 0 12 % N
% Pro: 0 0 0 12 0 0 0 0 0 12 12 0 0 12 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 23 23 67 0 56 34 89 67 12 0 0 12 0 67 0 % S
% Thr: 0 0 12 12 0 12 0 12 0 12 34 0 0 0 0 % T
% Val: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _