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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGD6
All Species:
12.73
Human Site:
S552
Identified Species:
35
UniProt:
Q6ZV73
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZV73
NP_060821.3
1430
160816
S552
C
A
Q
N
R
G
V
S
S
S
F
D
M
P
K
Chimpanzee
Pan troglodytes
XP_001142099
1430
160830
S552
C
A
Q
N
R
G
V
S
S
S
F
D
M
P
K
Rhesus Macaque
Macaca mulatta
XP_001106559
1431
160939
S553
C
A
Q
N
R
G
V
S
S
S
S
D
M
P
K
Dog
Lupus familis
XP_854794
1471
164544
S605
C
A
Q
N
L
N
M
S
S
S
F
D
M
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZL1
1399
155151
A530
P
P
N
H
G
A
S
A
S
P
F
D
M
P
N
Rat
Rattus norvegicus
NP_001131117
1406
157019
P536
P
S
N
H
G
M
S
P
S
S
F
D
M
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510070
1533
171433
K665
L
S
T
K
D
M
P
K
R
A
S
E
K
P
V
Chicken
Gallus gallus
XP_416149
1453
162099
L586
P
A
R
E
Q
G
A
L
S
S
S
D
I
P
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001093450
1315
147421
W499
P
P
Q
E
K
P
S
W
R
V
A
L
P
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.6
83.6
N.A.
74.3
75
N.A.
59.5
62.2
N.A.
41.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.6
88.1
N.A.
82
83.1
N.A.
70.1
74.8
N.A.
58.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
33.3
40
N.A.
6.6
40
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
46.6
53.3
N.A.
26.6
66.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
56
0
0
0
12
12
12
0
12
12
0
0
0
0
% A
% Cys:
45
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
0
0
0
0
0
78
0
0
0
% D
% Glu:
0
0
0
23
0
0
0
0
0
0
0
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
56
0
0
0
0
% F
% Gly:
0
0
0
0
23
45
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% I
% Lys:
0
0
0
12
12
0
0
12
0
0
0
0
12
0
45
% K
% Leu:
12
0
0
0
12
0
0
12
0
0
0
12
0
0
0
% L
% Met:
0
0
0
0
0
23
12
0
0
0
0
0
67
0
0
% M
% Asn:
0
0
23
45
0
12
0
0
0
0
0
0
0
0
23
% N
% Pro:
45
23
0
0
0
12
12
12
0
12
0
0
12
89
0
% P
% Gln:
0
0
56
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
12
0
34
0
0
0
23
0
0
0
0
0
12
% R
% Ser:
0
23
0
0
0
0
34
45
78
67
34
0
0
12
0
% S
% Thr:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
34
0
0
12
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _